SCHEMBL6885174

SCHEMBL6885174

CCCCCS(=O)(=O)OCc1ccccc1[N+](=O)[O-]

nearest known ligand 0.45

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.45
HTT P42858 1/20 0.45
MAOB P27338 1/20 0.44
TSHR P16473 1/20 0.44
TXNRD1 Q16881 4/20 0.43
GSR P00390 1/20 0.42
KDM4E B2RXH2 1/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
LMNA P02545 1/20 0.42
HPGD P15428 1/20 0.41
CA12 O43570 1/20 0.39
CA9 Q16790 1/20 0.39
KMT2A Q03164 3/20 0.39
MEN1 O00255 2/20 0.39
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10400333 0.99 TXNRD1 (0.45) ALDH1A1HTTMAOBTSHRTXNRD1
SCHEMBL10401228 0.99 TXNRD1 (0.45) ALDH1A1HTTMAOBTSHRTXNRD1
SCHEMBL16139544 0.96 ALDH1A1 (0.46) ALDH1A1HTTMAOBTSHRTXNRD1
SCHEMBL14411092 0.85 ALDH1A1 (0.55) ALDH1A1HTTMAOBTSHRHPGD
SCHEMBL1089020 0.79 ALDH1A1 (0.51) ALDH1A1HTTMAOBTSHRHPGD
SCHEMBL10401151 0.79 CA2 (0.44) ALDH1A1HTTMAOBKDM4ESMN1; SMN2
SCHEMBL8430876 0.79 ALDH1A1 (0.55) ALDH1A1HTTMAOBTSHRHPGD
SCHEMBL6885171 0.78 ALDH1A1 (0.44) ALDH1A1HTTTSHRKDM4ESMN1; SMN2
SCHEMBL8964981 0.77 MAOB (0.45) ALDH1A1HTTMAOBKDM4ESMN1; SMN2
SCHEMBL2244893 0.77 ALDH1A1 (0.56) ALDH1A1TSHRSMN1; SMN2LMNAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6723483-B1 Sulfonium salt compounds WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2004-04-20 US disclosed
EP-1113005-B1 Sulfonium salt compounds WAKO PURE CHEM IND LTD (JP) 2003-08-06 EP disclosed
EP-1238969-A2 Sulfonium salt compounds Wako Pure Chemical Industries, Ltd. (JP) 2002-09-11 EP disclosed
EP-1113005-A1 Sulfonium salt compounds Wako Pure Chemical Industries, Ltd. (JP) 2001-07-04 EP disclosed