Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 8/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ODC1 | P11926 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL14860334 | 0.92 | CYP3A4 (0.40) | CYP3A4HTTCES1DNM1MEN1 | |
| SCHEMBL6885240 | 0.92 | THRB (0.40) | CYP3A4THRBCES1DNM1MEN1 | |
| SCHEMBL26711992 | 0.90 | CYP3A4 (0.43) | CYP3A4THRBHTTCES1DNM1 | |
| SCHEMBL12201021 | 0.87 | CYP3A4 (0.38) | CYP3A4THRBCES1DNM1MEN1 | |
| SCHEMBL9881090 | 0.82 | THRB (0.45) | THRBCES1 | |
| SCHEMBL19655569 | 0.81 | CYP3A4 (0.46) | CYP3A4HTTCES1DNM1MEN1 | |
| SCHEMBL25657907 | 0.80 | CYP3A4 (0.38) | CYP3A4THRBCES1TSHRODC1 | |
| SCHEMBL665387 | 0.78 | TSHR (0.44) | CYP3A4THRBHTTCES1MEN1 | |
| SCHEMBL25723415 | 0.78 | THRB (0.42) | THRB | |
| SCHEMBL18165336 | 0.78 | OPRM1 (0.37) | CYP3A4THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6765056-B2 | ALDEHYDE-FUNCTIONAL POLYURETHANE COMPRISING DISPERSING GROUPS, AND A LOW MOLECULAR WEIGHT ALDEHYDE-REACTIVE CROSSLINKER SELECTED FROM POLYAMINES AND CYANO, SULFO, KETO-, PHOSPHONO, OR NITRO-FUNCTIONAL COMPOUNDS; REFINISHING CARS | AKZO NOBEL N.V. (NL) | 2004-07-20 | — | — | US | disclosed |
| US-20020040093-A1 | Aqueous cross-linkable binder composition and its use in the production of lacquer coatings | AKZO NOBEL N. V. (NL) | 2002-04-04 | — | — | US | disclosed |