Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 12/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6886723 | 0.79 | MAOB (0.37) | — | |
| SCHEMBL6884382 | 0.76 | MAOB (0.50) | RAB9A | |
| SCHEMBL6878729 | 0.75 | FFAR1 (0.37) | — | |
| SCHEMBL6155986 | 0.74 | PPARA (0.39) | HPGD | |
| SCHEMBL8615592 | 0.73 | ACACB (0.57) | ACACBRAB9ALMNAHPGD | |
| SCHEMBL6886628 | 0.70 | — | — | |
| SCHEMBL7985128 | 0.70 | ACE2 (0.34) | — | |
| SCHEMBL8154161 | 0.70 | ACACB (0.56) | ACACB | |
| SCHEMBL12182347 | 0.69 | ACACB (0.57) | ACACBRAB9AHPGD | |
| SCHEMBL5736748 | 0.68 | GABRA1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | disclosed |