Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.34 |
| ▸ | CAMKK1 | Q8N5S9 | 1/20 | 0.31 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5736748 | 0.74 | GABRA1 (0.31) | — | |
| SCHEMBL7985131 | 0.74 | ACE2 (0.33) | ACE2 | |
| SCHEMBL6885341 | 0.70 | ACACB (0.43) | — | |
| SCHEMBL7984067 | 0.69 | RARB (0.36) | ACE2CAMKK1CAMKK2 | |
| SCHEMBL10412862 | 0.68 | GABRP (0.41) | CAMKK2 | |
| SCHEMBL7980972 | 0.67 | SLC6A2 (0.33) | ACE2 | |
| SCHEMBL6673750 | 0.66 | ALDH1A1 (0.41) | — | |
| SCHEMBL394617 | 0.66 | XDH (0.46) | — | |
| SCHEMBL2853358 | 0.65 | HSD17B10 (0.45) | — | |
| SCHEMBL7987639 | 0.65 | HNF4A (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6303785-B1 | SUBSTITUTED N-CYCLOPROPYLTETRAHYDROISOQUINOLINES | ALLERGAN SALES, INC. | 2001-10-16 | — | — | US | disclosed |