Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.37 |
| ▸ | PTGES | O14684 | 11/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6885577 | 0.91 | FFAR1 (0.43) | FFAR1 | |
| SCHEMBL6884922 | 0.85 | HMGCR (0.33) | FFAR1PTGES | |
| SCHEMBL6878841 | 0.81 | HDAC1 (0.40) | FFAR1PTGESHDAC1HDAC6 | |
| SCHEMBL6885341 | 0.75 | ACACB (0.43) | — | |
| SCHEMBL6885094 | 0.74 | CYP4F2 (0.42) | HDAC1HDAC6PDE3BPDE3AP2RY12 | |
| SCHEMBL6885108 | 0.74 | CYP4F2 (0.42) | HDAC1HDAC6PDE3BPDE3AP2RY12 | |
| SCHEMBL29165966 | 0.73 | FFAR1 (0.48) | FFAR1HDAC1HDAC6PDE3BPDE3A | |
| SCHEMBL6885404 | 0.71 | CYSLTR2 (0.48) | FFAR1 | |
| SCHEMBL6878730 | 0.71 | FFAR1 (0.40) | FFAR1PTGESHDAC1HDAC6PDE3B | |
| SCHEMBL4841588 | 0.70 | CYSLTR2 (0.42) | HDAC1HDAC6PDE3BPDE3AP2RY12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | disclosed |