Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.69 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.49 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.48 |
| ▸ | CASR | P41180 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15890728 | 0.85 | MAPKAPK2 (0.50) | ALDH1A1GAAMAPTPFKFB3SOS1 | |
| SCHEMBL22439917 | 0.85 | MAPKAPK2 (0.50) | ALDH1A1GAAMAPTPFKFB3SOS1 | |
| SCHEMBL7666865 | 0.83 | ALDH1A1 (0.50) | ALDH1A1GAAMAPTNPSR1CASR | |
| SCHEMBL15137443 | 0.82 | ALDH1A1 (1.00) | ALDH1A1GAAMAPTNPSR1MEN1 | |
| SCHEMBL3172125 | 0.82 | ALDH1A1 (1.00) | ALDH1A1GAAMAPTNPSR1MEN1 | |
| SCHEMBL15004002 | 0.82 | ALDH1A1 (1.00) | ALDH1A1GAAMAPTNPSR1MEN1 | |
| SCHEMBL15326794 | 0.80 | ALDH1A1 (0.72) | ALDH1A1GAAMAPTNPSR1MEN1 | |
| SCHEMBL30518062 | 0.80 | ALDH1A1 (0.47) | ALDH1A1GAAMAPTNPSR1MEN1 | |
| SCHEMBL6687727 | 0.79 | ALDH1A1 (0.82) | ALDH1A1GAAMAPTNPSR1MEN1 | |
| SCHEMBL15003942 | 0.79 | ALDH1A1 (0.82) | ALDH1A1GAAMAPTNPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2836497-B1 | CATALYST COMPOUNDS | UNIV LIVERPOOL (GB) | 2016-03-23 | — | — | EP | disclosed |
| US-9212199-B2 | Catalyst compounds | THE UNIVERSITY OF LIVERPOOL (GB) | 2015-12-15 | — | — | US | disclosed |
| US-9212199-B2 | Catalyst compounds | THE UNIVERSITY OF LIVERPOOL (GB) | 2015-12-15 | — | — | US | disclosed |
| US-20150080592-A1 | CATALYST COMPOUNDS | THE UNIVERSITY OF LIVERPOOL (GB) | 2015-03-19 | — | — | US | disclosed |
| US-20150080592-A1 | CATALYST COMPOUNDS | THE UNIVERSITY OF LIVERPOOL (GB) | 2015-03-19 | — | — | US | disclosed |
| US-20040147762-A1 | Asymmetric reductive amination of ketones | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040147762-A1 | Asymmetric reductive amination of ketones | AKR7A2, PDK2, AADAT | ALDH1A1 205/4885GAA 3335/4885MAPT 3941/4885 |
| US-20150080592-A1 | CATALYST COMPOUNDS | IDH3B, IDH2, NQO1 | ALDH1A1 261/4885GAA 3482/4885MAPT 4290/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.