Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 6/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 4/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6885569 | 0.90 | FFAR1 (0.46) | FFAR1FFAR4 | |
| SCHEMBL6884926 | 0.84 | FFAR1 (0.34) | FFAR1FFAR4 | |
| SCHEMBL6878844 | 0.81 | MTNR1A (0.41) | FFAR1HDAC6HDAC1 | |
| SCHEMBL7777946 | 0.78 | FFAR1 (0.35) | FFAR1FFAR4 | |
| SCHEMBL6155420 | 0.75 | ACACB (0.43) | — | |
| SCHEMBL6885100 | 0.75 | CYP4F2 (0.44) | HDAC6HDAC1PDE3BPDE3AP2RY12 | |
| SCHEMBL6156487 | 0.71 | CYSLTR2 (0.50) | FFAR1FFAR4 | |
| SCHEMBL6878729 | 0.71 | FFAR1 (0.37) | FFAR1HDAC6HDAC1PTGESPDE3B | |
| SCHEMBL29165966 | 0.71 | FFAR1 (0.48) | FFAR1HDAC6HDAC1FFAR4PDE3B | |
| SCHEMBL22626719 | 0.71 | FFAR1 (0.44) | FFAR1PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | disclosed |