Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 4/20 | 0.42 |
| ▸ | FOS | P01100 | 1/20 | 0.42 |
| ▸ | JUN | P05412 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6882901 | 0.88 | METAP2 (0.53) | METAP2ALDH1A1LMNAMAPTRAB9A | |
| SCHEMBL6882899 | 0.88 | METAP2 (0.53) | METAP2ALDH1A1LMNAMAPTRAB9A | |
| SCHEMBL6884951 | 0.73 | ALDH1A1 (0.45) | HPGDKDM4EALDH1A1MAOBFOS | |
| SCHEMBL6886683 | 0.70 | METAP2 (0.49) | METAP2ALDH1A1LMNAMAPTRAB9A | |
| SCHEMBL6886738 | 0.70 | METAP2 (0.47) | METAP2ALDH1A1LMNAMAPTRAB9A | |
| SCHEMBL6886678 | 0.70 | METAP2 (0.49) | METAP2ALDH1A1LMNAMAPTRAB9A | |
| SCHEMBL6884374 | 0.70 | METAP2 (0.47) | METAP2ALDH1A1LMNAMAPTRAB9A | |
| SCHEMBL7459014 | 0.70 | METAP2 (0.77) | METAP2ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL13799963 | 0.70 | METAP2 (0.77) | METAP2ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL23710407 | 0.69 | METAP2 (0.81) | METAP2ALDH1A1LMNAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6803382-B2 | 1-OXASPIRO(2,5)OCTAN-6-OL DERIVATIVES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2004-10-12 | — | — | US | disclosed |