Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6156192 | 0.87 | MGLL (0.39) | DHFRMGLLCNR1CNR2BCHE | |
| SCHEMBL6156767 | 0.85 | MGLL (0.35) | MGLLCNR1CNR2LMNAHPGD | |
| SCHEMBL6155888 | 0.84 | HSP90AA1 (0.38) | DHFRKDM4CHPGDNPC1RAB9A | |
| SCHEMBL6879672 | 0.82 | HMGCR (0.33) | DHFRKDM4C | |
| SCHEMBL6881436 | 0.78 | HMGCR (0.37) | DHFRKDM4CNPC1RAB9A | |
| SCHEMBL6879551 | 0.78 | HMGCR (0.36) | DHFRKDM4CNPC1RAB9A | |
| SCHEMBL6884487 | 0.76 | HMGCR (0.35) | DHFR | |
| SCHEMBL6155756 | 0.76 | HMGCR (0.36) | DHFRKDM4CNPC1RAB9A | |
| SCHEMBL6886674 | 0.71 | BACE1 (0.33) | — | |
| SCHEMBL6886189 | 0.70 | BACE1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | disclosed |