Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6155888 | 0.85 | HSP90AA1 (0.38) | HMGCRDHFRKDM4C | |
| SCHEMBL6155243 | 0.82 | HMGCR (0.41) | HMGCR | |
| SCHEMBL6155238 | 0.82 | HMGCR (0.41) | HMGCR | |
| SCHEMBL6885859 | 0.82 | DHFR (0.38) | DHFRKDM4C | |
| SCHEMBL6879551 | 0.80 | HMGCR (0.36) | HMGCRDHFRKDM4C | |
| SCHEMBL6881436 | 0.78 | HMGCR (0.37) | HMGCRDHFRKDM4C | |
| SCHEMBL6155756 | 0.77 | HMGCR (0.36) | HMGCRDHFRKDM4C | |
| SCHEMBL6884487 | 0.76 | HMGCR (0.35) | HMGCRDHFR | |
| SCHEMBL6154762 | 0.73 | HMGCR (0.40) | HMGCRDHFRKDM4C | |
| SCHEMBL6878864 | 0.71 | HMGCR (0.35) | HMGCRDHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | disclosed |