Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IP6K1 | Q92551 | 1/20 | 0.44 |
| ▸ | WDR5 | P61964 | 4/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 9/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 9/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 9/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.37 |
| ▸ | IKBKB | O14920 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6887531 | 0.83 | SIRT6 (0.54) | WDR5MAPTMAPK1SIRT6 | |
| SCHEMBL1558664 | 0.83 | MAPT (0.55) | IP6K1ADRA2CKDM4EGAAMAPT | |
| SCHEMBL17779230 | 0.80 | IP6K1 (0.68) | IP6K1KDM4EGAAMAPTMAPK1 | |
| SCHEMBL3535324 | 0.80 | MAPT (0.45) | ADRA2AADRA2BADRA2CKDM4EGAA | |
| SCHEMBL3535320 | 0.80 | MAPT (0.45) | ADRA2AADRA2BADRA2CKDM4EGAA | |
| SCHEMBL6887548 | 0.80 | IP6K1 (0.43) | IP6K1IKBKB | |
| SCHEMBL17779283 | 0.79 | IP6K1 (0.66) | IP6K1KDM4EGAAMAPTMAPK1 | |
| SCHEMBL691990 | 0.78 | IP6K1 (0.47) | IP6K1KDM4EGAAMAPTMAPK1 | |
| SCHEMBL1231926 | 0.76 | LGMN (0.54) | IP6K1MAPTMAPK1JAK2JAK1 | |
| SCHEMBL5804163 | 0.76 | WDR5 (0.43) | WDR5ADRA2AADRA2BADRA2CKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011045258-A1 | CONDENSED AZINE - DERIVATIVES FOR THE TREATMENT OF DISEASES RELATED TO THE ACETYLCHOLINE RECEPTOR | N.V. ORGANON (NL) | 2011-04-21 | — | — | WO | disclosed |