Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 5/20 | 0.49 |
| ▸ | FAP | Q12884 | 11/20 | 0.47 |
| ▸ | PREP | P48147 | 3/20 | 0.45 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.45 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 2/20 | 0.45 |
| ▸ | HTR7 | P34969 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6887774 | 0.82 | DPP4 (0.55) | DPP4FAPPREPDPP8DPP9 | |
| SCHEMBL22811409 | 0.80 | KMT2A (0.53) | FAPPREPDPP8DPP9 | |
| SCHEMBL22811104 | 0.80 | KMT2A (0.53) | FAPPREPDPP8DPP9 | |
| SCHEMBL29359148 | 0.75 | DPP4 (0.63) | DPP4FAPPREP | |
| SCHEMBL11386628 | 0.75 | PREP (0.53) | FAPPREP | |
| SCHEMBL12031885 | 0.75 | KMT2A (0.58) | FAPPREPDPP8DPP9 | |
| SCHEMBL12031796 | 0.75 | FAP (0.50) | FAPPREP | |
| SCHEMBL30493625 | 0.74 | DPP4 (0.60) | DPP4FAPPREP | |
| SCHEMBL31324091 | 0.74 | DPP4 (0.64) | DPP4FAPPREPDPP8DPP9 | |
| SCHEMBL31324097 | 0.73 | DPP4 (0.55) | DPP4FAPPREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011002808-A1 | HCV PROTEASE INHIBITORS AND USES THEREOF | AVILA THERAPEUTICS, INC. (US) | 2011-01-06 | — | — | WO | disclosed |
| WO-2009082701-A1 | HCV PROTEASE INHIBITORS AND USES THEREOF | AVILA THERAPEUTICS, INC. (US) | 2009-07-02 | — | — | WO | disclosed |