Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 7/20 | 0.55 |
| ▸ | FAP | Q12884 | 10/20 | 0.50 |
| ▸ | PREP | P48147 | 5/20 | 0.50 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.50 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | HTR7 | P34969 | 1/20 | 0.50 |
| ▸ | ACE | P12821 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6886544 | 0.82 | DPP4 (0.49) | DPP4FAPPREPDPP8DPP9 | |
| SCHEMBL29359148 | 0.78 | DPP4 (0.63) | DPP4FAPPREPACE | |
| SCHEMBL31324091 | 0.77 | DPP4 (0.64) | DPP4FAPPREPDPP8DPP9 | |
| SCHEMBL13071509 | 0.76 | DPP4 (0.57) | DPP4HTR1AHTR7ACE | |
| SCHEMBL31324117 | 0.76 | DPP4 (0.60) | DPP4FAPPREPACE | |
| SCHEMBL16381886 | 0.75 | RAB9A (0.58) | — | |
| SCHEMBL19692655 | 0.75 | DPP4 (0.51) | DPP4FAPPREPACE | |
| SCHEMBL15129897 | 0.75 | DPP4 (0.51) | DPP4FAPPREPACE | |
| SCHEMBL19225842 | 0.74 | DPP4 (0.47) | DPP4FAPPREPDPP8DPP9 | |
| SCHEMBL9518270 | 0.74 | PREP (0.68) | DPP4PREPDPP8DPP9ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011002808-A1 | HCV PROTEASE INHIBITORS AND USES THEREOF | AVILA THERAPEUTICS, INC. (US) | 2011-01-06 | — | — | WO | disclosed |