Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6886666 | 0.89 | CYSLTR2 (0.40) | NPC1RAB9AHSP90AA1L3MBTL1MRGPRX4 | |
| SCHEMBL6155146 | 0.88 | NPC1 (0.47) | NPC1RAB9AHSP90AA1L3MBTL1PTPN1 | |
| SCHEMBL6155468 | 0.79 | NPC1 (0.42) | NPC1RAB9AHSP90AA1L3MBTL1MEN1 | |
| SCHEMBL6155463 | 0.79 | VDR (0.44) | NPC1RAB9AHSP90AA1L3MBTL1MEN1 | |
| SCHEMBL6154639 | 0.77 | CYSLTR2 (0.43) | KMT2ASMN1; SMN2MRGPRX4FFAR1 | |
| SCHEMBL6881337 | 0.77 | CYSLTR2 (0.42) | MRGPRX4FFAR1 | |
| SCHEMBL27534810 | 0.76 | MRGPRX4 (0.33) | MRGPRX4 | |
| SCHEMBL2106608 | 0.74 | MRGPRX4 (0.42) | SMN1; SMN2MRGPRX4FFAR1 | |
| SCHEMBL15613848 | 0.74 | NPC1 (0.59) | NPC1RAB9AHSP90AA1L3MBTL1MEN1 | |
| SCHEMBL6881292 | 0.72 | MRGPRX4 (0.41) | MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1282636-C | Vitamin D analogues | GALDERMA RES & DEV (FR) | 2006-11-01 | — | — | CN | disclosed |
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | disclosed |
| CN-1332711-A | Vitamin D analogues | GALDERMA RES & DEV (FR) | 2002-01-23 | — | — | CN | disclosed |