Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6886939 | 1.00 | NPC1 (0.35) | NPC1MAPTRAB9AMEN1KMT2A | |
| SCHEMBL6562874 | 0.89 | CYP4F2 (0.34) | RAB9ASMN1; SMN2MRGPRX4CYP4F2CYP4A11 | |
| SCHEMBL6562882 | 0.89 | CYP4F2 (0.34) | RAB9ASMN1; SMN2MRGPRX4CYP4F2CYP4A11 | |
| SCHEMBL6881304 | 0.87 | MRGPRX4 (0.46) | NPC1MAPTRAB9ASMN1; SMN2MRGPRX4 | |
| SCHEMBL6881311 | 0.87 | MRGPRX4 (0.46) | NPC1MAPTRAB9ASMN1; SMN2MRGPRX4 | |
| SCHEMBL6886887 | 0.87 | MRGPRX4 (0.32) | NPC1MAPTRAB9AMEN1KMT2A | |
| SCHEMBL6886891 | 0.87 | MRGPRX4 (0.32) | NPC1MAPTRAB9AMEN1KMT2A | |
| SCHEMBL6888099 | 0.83 | ALOX5AP (0.35) | NPC1MAPTRAB9AMEN1KMT2A | |
| SCHEMBL6888103 | 0.83 | ALOX5AP (0.35) | NPC1MAPTRAB9AMEN1KMT2A | |
| SCHEMBL6563996 | 0.81 | VDR (0.44) | CYP4F2CYP4A11MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6706725-B1 | BIAROMATIC COMPOUNDS WHICH ARE VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2004-03-16 | — | — | US | disclosed |