SCHEMBL6887228

SCHEMBL6887228

Cc1c(C)c(C)c2c(c1C)C=c1cc3c(cc1C2=O)=Cc1ccccc1C3=O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDC25B P30305 3/20 0.37
CDC25A P30304 2/20 0.37
ELANE P08246 2/20 0.34
ALDH1A1 P00352 6/20 0.33
L3MBTL1 Q9Y468 4/20 0.33
MAPK1 P28482 4/20 0.33
CYP3A4 P08684 3/20 0.33
RAB9A P51151 3/20 0.33
SMN1; SMN2 Q16637 3/20 0.33
TSHR P16473 2/20 0.33
TTR P02766 2/20 0.33
HBB P68871 2/20 0.33
NPC1 O15118 1/20 0.33
CASP3 P42574 1/20 0.33
SENP7 Q9BQF6 1/20 0.33
SENP6 Q9GZR1 1/20 0.33
MEN1 O00255 4/20 0.32
KMT2A Q03164 4/20 0.32
MAPT P10636 4/20 0.32
LMNA P02545 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3444764 0.80 MEN1 (0.48) CDC25BCDC25AELANEALDH1A1L3MBTL1
SCHEMBL9510889 0.67 MEN1 (0.55) CDC25BCDC25AELANEALDH1A1L3MBTL1
SCHEMBL2452850 0.67 IDO1 (0.41) CDC25BCDC25AALDH1A1TTRMEN1
SCHEMBL5207877 0.67 CDC25B (0.36) CDC25BCDC25AELANEALDH1A1MEN1
SCHEMBL6441256 0.65 ELANE (0.48) ELANEALDH1A1SMN1; SMN2ACHEMAOB
SCHEMBL6655299 0.65 CDC25B (0.34) CDC25BCDC25AALDH1A1MEN1KMT2A
SCHEMBL4818463 0.65 CDC25B (0.34) CDC25BCDC25AALDH1A1MEN1KMT2A
SCHEMBL27937068 0.64
SCHEMBL678100 0.64 MAPT (0.61) CDC25BCDC25AELANEALDH1A1L3MBTL1
SCHEMBL9803179 0.64 MAPT (0.54) CDC25BCDC25AELANEALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1430008-A2 PROCESS FOR PREPARING PENTACENE DERIVATIVES 3M Innovative Properties Company (US) 2004-06-23 EP disclosed
WO-2003027050-A2 PROCESS FOR PREPARING PENTACENE DERIVATIVES 3M INNOVATIVE PROPERTIES COMPANY (US) 2003-04-03 WO disclosed