SCHEMBL6887346

SCHEMBL6887346

CCCCCC1CCNC1=O

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 5/20 0.43
CCR2 P41597 7/20 0.42
CYP1A2 P05177 3/20 0.40
CCR1 P32246 1/20 0.37
CCR5 P51681 1/20 0.37
CXCR4 P61073 1/20 0.37
ALDH1A1 P00352 2/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
HLCS P50747 1/20 0.36
KDM4E B2RXH2 1/20 0.35
MEN1 O00255 1/20 0.35
MAPT P10636 1/20 0.35
PKM P14618 1/20 0.35
HPGD P15428 1/20 0.35
KMT2A Q03164 1/20 0.35
NAAA Q02083 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24919786 0.98 CYP19A1 (0.45) CYP19A1CCR2CYP1A2CCR1CCR5
SCHEMBL8676129 0.98 CYP19A1 (0.45) CYP19A1CCR2CYP1A2CCR1CCR5
SCHEMBL5857915 0.98 CYP19A1 (0.45) CYP19A1CCR2CYP1A2CCR1CCR5
SCHEMBL17187540 0.98 CYP19A1 (0.45) CYP19A1CCR2CYP1A2CCR1CCR5
SCHEMBL2484772 0.94 CYP19A1 (0.42) CYP19A1CCR2CYP1A2CCR1CCR5
SCHEMBL1401505 0.89 CCR2 (0.46) CYP19A1CCR2CYP1A2CCR1CCR5
SCHEMBL7622441 0.87 CCR2 (0.47) CYP19A1CCR2CYP1A2CCR1CCR5
SCHEMBL181231 0.87 CCR2 (0.51) CYP19A1CCR2CYP1A2CCR1CCR5
SCHEMBL9978692 0.87 CCR2 (0.47) CYP19A1CCR2CYP1A2CCR1CCR5
SCHEMBL9003899 0.86 CCR2 (0.52) CYP19A1CCR2CYP1A2CCR1CCR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1198800-C 2- (2-chlorophenyl) -3, 4-dihydro-2H-pyrrole derivatives BAYER AG (DE) 2005-04-27 CN claimed
CN-1323304-A 2-hetaryl-3,4-dihydro-2h-pyrrole derivatives BAYER AG (DE) 2001-11-21 CN claimed
CN-1309636-A 2-(2-chlorophenyl)-3,4-dihydro-2H-pyrrol derivs. BAYER AG (DE) 2001-08-22 CN claimed
CN-111770783-A Improved impurity removal process 塔明克公司 2020-10-13 CN disclosed
CN-106414534-B It is suitable as the urea preparation of the stable storage of rheology control agent 比克化学股份有限公司 2019-05-07 CN disclosed
EP-3131941-B1 RHEOLOGY CONTROL AGENTS COMPRISING AN ACTIVE SUBSTANCE COMBINATION BYK CHEMIE GMBH (DE) 2018-02-07 EP disclosed
EP-3131941-A1 RHEOLOGY CONTROL AGENTS COMPRISING AN ACTIVE SUBSTANCE COMBINATION BYK-Chemie GmbH (DE) 2017-02-22 EP disclosed
EP-3131939-A1 STORAGE-STABLE UREA PREPARATIONS WHICH ARE SUITABLE AS RHEOLOGY CONTROL AGENTS BYK-Chemie GmbH (DE) 2017-02-22 EP disclosed
CN-106414534-A Storage-stable urea preparations which are suitable as rheology control agents 比克化学股份有限公司 2017-02-15 CN disclosed
WO-2015158792-A1 RHEOLOGY CONTROL AGENTS COMPRISING AN ACTIVE SUBSTANCE COMBINATION BYK-CHEMIE GMBH (DE) 2015-10-22 WO disclosed
WO-2015158794-A1 STORAGE-STABLE UREA PREPARATIONS WHICH ARE SUITABLE AS RHEOLOGY CONTROL AGENTS BYK-CHEMIE GMBH (DE) 2015-10-22 WO disclosed
CN-1323304-A 2-hetaryl-3,4-dihydro-2h-pyrrole derivatives BAYER AG (DE) 2001-11-21 CN disclosed
CN-1309636-A 2-(2-chlorophenyl)-3,4-dihydro-2H-pyrrol derivs. BAYER AG (DE) 2001-08-22 CN disclosed
US-5981567-A ARTHROPODICIDAL OR NEMATICIDAL COMPOSITION BAYER AKTIENGESELLSCHAFT (DE) 1999-11-09 US disclosed
US-5972237-A USED AS COLD BLEACH ACTIVATORS OR OPTICAL BRIGHTENERS IN DETERGENTS, CLEANERS AND BLEACHES AND IN DISINFECTANTS BASF AKTIENGESELLSCHAFT (DE) 1999-10-26 US disclosed
WO-1990007497-A1 PROCESS FOR THE PREPARATION OF 3-ACYLPYRROLIDONES ICI AMERICAS INC. (US) 1990-07-12 WO disclosed
WO-1990007497-A1 PROCESS FOR THE PREPARATION OF 3-ACYLPYRROLIDONES ICI AMERICAS INC. (US) 1990-07-12 WO disclosed
US-4874873-A Process for the preparation of 3-acylpyrrolidones ICI AMERICAS INC. (US) 1989-10-17 US disclosed
US-4874873-A Process for the preparation of 3-acylpyrrolidones ICI AMERICAS INC. (US) 1989-10-17 US disclosed
US-4874873-A Process for the preparation of 3-acylpyrrolidones ICI AMERICAS INC. (US) 1989-10-17 US disclosed