SCHEMBL2484772

SCHEMBL2484772

CCCCC1CCNC1=O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 5/20 0.42
KDM4E B2RXH2 1/20 0.40
MEN1 O00255 1/20 0.40
ALDH1A1 P00352 1/20 0.40
MAPT P10636 1/20 0.40
PKM P14618 1/20 0.40
HPGD P15428 1/20 0.40
KMT2A Q03164 1/20 0.40
CCR2 P41597 5/20 0.38
NFKB1 P19838 1/20 0.37
NFKB2 Q00653 1/20 0.37
RELA Q04206 1/20 0.37
NAAA Q02083 1/20 0.35
MMP1 P03956 1/20 0.35
MMP3 P08254 1/20 0.35
MMP9 P14780 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
CCR1 P32246 1/20 0.35
CCR5 P51681 1/20 0.35
CXCR4 P61073 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6887346 0.94 CYP19A1 (0.43) CYP19A1KDM4EMEN1ALDH1A1MAPT
SCHEMBL5857915 0.92 CYP19A1 (0.45) CYP19A1ALDH1A1CCR2NAAACCR1
SCHEMBL8676129 0.92 CYP19A1 (0.45) CYP19A1ALDH1A1CCR2NAAACCR1
SCHEMBL17187540 0.92 CYP19A1 (0.45) CYP19A1ALDH1A1CCR2NAAACCR1
SCHEMBL24919786 0.92 CYP19A1 (0.45) CYP19A1ALDH1A1CCR2NAAACCR1
SCHEMBL5754395 0.89 CCR2 (0.42) CYP19A1KDM4EMEN1ALDH1A1MAPT
SCHEMBL2485204 0.88
SCHEMBL30522495 0.88
SCHEMBL8376974 0.88
SCHEMBL1706310 0.87 CCR2 (0.48) CYP19A1KDM4EMEN1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017012963-A1 POLYMERIZABLE FATTY ACID-DERIVATIVE-MONOMERS WITH TERMINAL OLEFINIC DOUBLE BONDS, POLYMERS CONTAINING SAME MONOMERS, PRODUCTION AND USE THEREOF BASF SE (DE) 2017-01-26 WO claimed
US-20080182773-A1 Thickeners Based on Polymers Comprising Amine Groups BASF AKTIENGESELLSCHAFT (DE) 2008-07-31 US claimed
EP-1863574-A1 THICKENER BASED ON AMINE GROUP-CONTAINING POLYMERS BASF AKTIENGESELLSCHAFT (DE) 2007-12-12 EP claimed
WO-2006100299-A1 THICKENER BASED ON AMINE GROUP-CONTAINING POLYMERS BASF AKTIENGESELLSCHAFT (DE) 2006-09-28 WO claimed
CN-119552574-A Method for using light absorbing release composition and method for preparing semiconductor device 奇美实业股份有限公司 2025-03-04 CN disclosed
US-20220402950-A1 SUBSTITUTED BENZIMIDAZOLES AS PAD4 INHIBITORS BRISTOL-MYERS SQUIBB COMPANY 2022-12-22 US disclosed
EP-2170964-B1 HIGH-CATION COPOLYMERS BASED ON QUATERNIZED NITROGEN-CONTAINING MONOMERS BASF SE (DE) 2017-02-22 EP disclosed
WO-2017012963-A1 POLYMERIZABLE FATTY ACID-DERIVATIVE-MONOMERS WITH TERMINAL OLEFINIC DOUBLE BONDS, POLYMERS CONTAINING SAME MONOMERS, PRODUCTION AND USE THEREOF BASF SE (DE) 2017-01-26 WO disclosed
US-8623343-B2 Highly cationic copolymers based on quaternized nitrogen-containing monomers BASF SE (DE) 2014-01-07 US disclosed
US-20130108959-A1 USE OF A COMPOSITION COMPRISING VINYL MONOMER-COMPRISING POLYMER, SOLVENT AND AT LEAST ONE HALOGEN-FREE BIOCIDE BASF SE (DE) 2013-05-02 US disclosed
WO-2013060679-A1 USE OF A COMPOSITION CONTAINING VINYL-LACTAM-CONTAINING POLYMER, SOLVENT AND AT LEAST ONE HALOGEN-FREE BIOCIDE AS A METAL-QUENCHING MEDIUM BASF SE (DE) 2013-05-02 WO disclosed
WO-2012065928-A1 AQUEOUS METAL QUENCHING MEDIUM BASF SE (DE) 2012-05-24 WO disclosed
US-6066666-A OPTIONALLY N-SUBSTITUTED 3-MONO- AND DI-SUBSTITUTED 2-PYRROLIDINONES AND THIOLACTAM ANALOGS; TREAT SEIZURES, ANXIETY, AND ENHANCING 4-AMINOBUTYRIC ACID (GABA)-INDUCED CHLORIDE CURRENTS AT GABA RECEPTOR/IONOPHORE COMPLEX WASHINGTON UNIVERSITY (US) 2000-05-23 US disclosed
WO-1999064426-A1 HETEROBICYCLIC AND TRICYCLIC NITRIC OXIDE SYNTHASE INHIBITORS G.D. SEARLE & CO. (US) 1999-12-16 WO disclosed
US-5776959-A Anticonvulsant and anxiolytic lactam and thiolactam derivatives WASHINGTON UNIVERSITY (US) 1998-07-07 US disclosed
EP-0005689-B1 LACTAM-N-ACETIC ACIDS, THEIR AMIDES, PROCESS FOR THEIR PREPARATION AND THERAPEUTIC COMPOSITIONS CONTAINING THEM U C B, S.A. (BE) 1981-03-18 EP disclosed
US-4221789-A MEMORY, CARDIOVASCULAR DISORDERS UCB, SOCIETE ANONYME (BE) 1980-09-09 US disclosed
EP-0005689-A1 Lactam-N-acetic acids, their amides, process for their preparation and therapeutic compositions containing them U C B, S.A. (BE) 1979-11-28 EP disclosed
US-4087270-A WEED CONTROL GAF CORPORATION (US) 1978-05-02 US disclosed
US-4086356-A Fungicidal-N-(3-halo-2,6-dinitro-4-trifluoromethylphenyl)-pyrrolidones GAF CORPORATION (US) 1978-04-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220402950-A1 SUBSTITUTED BENZIMIDAZOLES AS PAD4 INHIBITORS PADI4, PADI1, PADI6 CYP19A1 1318/4885KDM4E 62/4885MEN1 4059/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.