Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | MAP2K1 | Q02750 | 3/20 | 0.43 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1668020 | 0.84 | MAPT (0.48) | CDK1ALDH1A1SMN1; SMN2HTTNPC1 | |
| SCHEMBL18631034 | 0.76 | PRSS1 (0.53) | ALDH1A1SMN1; SMN2POLBMAPT | |
| SCHEMBL31638149 | 0.76 | ALDH1A1 (0.57) | ALDH1A1RAB9AMAPT | |
| SCHEMBL31441967 | 0.76 | PRSS1 (0.53) | ALDH1A1SMN1; SMN2POLBMAPT | |
| SCHEMBL6035694 | 0.74 | MAP2K1 (0.47) | MAP2K1MAP2K2ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL8384101 | 0.73 | MGLL (0.53) | ALDH1A1SMN1; SMN2HTTNPC1LMNA | |
| SCHEMBL275456 | 0.73 | DTYMK (0.62) | ALDH1A1CYP3A4LMNA | |
| SCHEMBL27770958 | 0.72 | CYP1A2 (0.41) | ALDH1A1SMN1; SMN2HTTGAAMAPT | |
| SCHEMBL12609468 | 0.72 | LMNA (0.53) | ALDH1A1SMN1; SMN2HTTLMNAPOLB | |
| SCHEMBL3585562 | 0.72 | MAPT (0.48) | CDK1ALDH1A1SMN1; SMN2HTTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011045258-A1 | CONDENSED AZINE - DERIVATIVES FOR THE TREATMENT OF DISEASES RELATED TO THE ACETYLCHOLINE RECEPTOR | N.V. ORGANON (NL) | 2011-04-21 | — | — | WO | disclosed |