Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 9/20 | 0.67 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.47 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6466856 | 0.80 | AR (1.00) | ARPTGDR2NOD1NOD2MEN1 | |
| SCHEMBL6887430 | 0.74 | AR (0.67) | ARALDH1A1SMN1; SMN2PKMHPGD | |
| SCHEMBL5594350 | 0.68 | CA1 (0.55) | NOD1ALDH1A1NOD2SMN1; SMN2LMNA | |
| SCHEMBL25811422 | 0.67 | MAPT (0.57) | ARPTGDR2NOD1ALDH1A1GAA | |
| SCHEMBL724342 | 0.66 | KMT2A (0.51) | ARNOD1ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL9666436 | 0.66 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2POLBLMNAMEN1 | |
| SCHEMBL6469421 | 0.65 | AR (1.00) | ARPTGDR2ALDH1A1LMNAKMT2A | |
| Methylamine SCHEMBL9267123 | 0.64 | MAPK1 (0.67) | ALDH1A1SMN1; SMN2POLBLMNAMEN1 | |
| SCHEMBL3895943 | 0.64 | AGTR1 (0.64) | ALDH1A1GAASMN1; SMN2POLBLMNA | |
| SCHEMBL11655146 | 0.64 | AGTR1 (0.64) | ALDH1A1GAASMN1; SMN2POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1466902-A1 | ANDROGEN RECEPTOR ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2004-10-13 | — | — | EP | disclosed |