Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.60 |
| ▸ | NPC1 | O15118 | 4/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.48 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.48 |
| ▸ | CACNA1I | Q9P0X4 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2615991 | 0.86 | POLB (0.49) | RAB9ANPC1SMN1; SMN2CACNA1GCACNA1H | |
| SCHEMBL17232475 | 0.86 | NPC1 (0.46) | RAB9ANPC1SMN1; SMN2CACNA1GCACNA1H | |
| SCHEMBL10247346 | 0.84 | GFER (0.60) | RAB9ANPC1SMN1; SMN2CACNA1GCACNA1H | |
| SCHEMBL1196573 | 0.82 | KDM4E (0.51) | RAB9ANPC1SMN1; SMN2CACNA1GCACNA1H | |
| SCHEMBL17229267 | 0.82 | NPC1 (0.43) | RAB9ANPC1SMN1; SMN2CACNA1GCACNA1H | |
| SCHEMBL1860285 | 0.81 | ALDH1A1 (0.66) | RAB9ANPC1SMN1; SMN2CACNA1GCACNA1H | |
| SCHEMBL29191568 | 0.79 | LMNA (0.57) | LMNAALDH1A1MAPTL3MBTL1MEN1 | |
| SCHEMBL24185986 | 0.77 | RAB9A (0.53) | RAB9ANPC1SMN1; SMN2CACNA1GCACNA1H | |
| SCHEMBL15172489 | 0.76 | RAB9A (0.60) | RAB9ANPC1SMN1; SMN2LMNAMAPT | |
| SCHEMBL5906334 | 0.75 | ALDH1A1 (0.48) | RAB9ANPC1SMN1; SMN2CACNA1GCACNA1H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8741934-B2 | Inhibitors of ion channels | PFIZER LIMITED (GB) | 2014-06-03 | — | — | US | disclosed |
| EP-1373191-A1 | ACYLATED INDANYL AMINES AND THEIR USE AS PHARMACEUTICALS | Aventis Pharma Deutschland GmbH (DE) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002064545-A1 | ACYLATED INDANYL AMINES AND THEIR USE AS PHARMACEUTICALS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-08-22 | — | — | WO | disclosed |