Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.48 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA9 | Q16790 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA7 | P43166 | 2/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | MYC | P01106 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL317626 | 0.81 | CA12 (0.42) | CA12CA1CA9PTPN1MYC | |
| SCHEMBL317703 | 0.81 | KEAP1 (0.43) | CA12CA1CA9CA2ALDH1A1 | |
| SCHEMBL31653832 | 0.81 | KEAP1 (0.43) | CA12CA1CA9CA2ALDH1A1 | |
| SCHEMBL610788 | 0.80 | CA12 (0.41) | CA12CA1CA9ALDH1A1PTPN1 | |
| SCHEMBL1464604 | 0.80 | CA12 (0.41) | CA12CA1CA9ALDH1A1TSHR | |
| SCHEMBL24425951 | 0.79 | CA12 (0.40) | CA12CA1CA9CA2CA7 | |
| SCHEMBL10627311 | 0.79 | MCL1 (0.42) | CA12CA1CA9PTPN1MYC | |
| SCHEMBL4256629 | 0.78 | GAA (0.41) | CA12CA1CA9ALDH1A1TSHR | |
| SCHEMBL9596295 | 0.78 | CA12 (0.39) | CA12CA1CA9ALDH1A1MYC | |
| SCHEMBL9262225 | 0.77 | GAA (0.55) | CA12CA1CA9ALDH1A1MYC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004087733-A2 | PREVENTION AND TREATMENT OF ALZHEIMER AMYLOID DEPOSITION | NEW YORK UNIVERSITY (US) | 2004-10-14 | — | — | WO | disclosed |
| EP-0170415-B1 | PHENANTHRIDINIUM ESTER AS A LABELLING COMPOUND IN LUMINOMETRIC IMMUNOASSAY | Mallinckrodt, Inc. (a Delaware corporation) (US) | 1988-04-20 | — | — | EP | disclosed |
| US-4687747-A | Phenanthridinium ester as a labelling compound in luminometric immunoassay | MALLINCKRODT, INC. (US) | 1987-08-18 | — | — | US | disclosed |
| EP-0170415-A1 | Phenanthridinium ester as a labelling compound in luminometric immunoassay | Mallinckrodt, Inc. (a Delaware corporation) (US) | 1986-02-05 | — | — | EP | disclosed |