Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.49 |
| ▸ | CA1 | P00915 | 4/20 | 0.49 |
| ▸ | CA2 | P00918 | 4/20 | 0.49 |
| ▸ | CA7 | P43166 | 4/20 | 0.49 |
| ▸ | CA9 | Q16790 | 4/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.49 |
| ▸ | CNR2 | P34972 | 2/20 | 0.46 |
| ▸ | P4HB | P07237 | 1/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | XDH | P47989 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6564927 | 0.82 | CA12 (0.53) | CA12CA1CA2CA9CNR2 | |
| SCHEMBL26681146 | 0.82 | SLC2A1 (0.52) | CA12CA1CA2CA7CA9 | |
| SCHEMBL6434807 | 0.80 | ERN1 (0.61) | CA12CA1CA2CA7CA9 | |
| SCHEMBL4700092 | 0.79 | EGFR (0.65) | CA12CA1CA2CA7CA9 | |
| SCHEMBL31337006 | 0.79 | EGFR (0.65) | CA12CA1CA2CA7CA9 | |
| SCHEMBL10832764 | 0.77 | CA1 (0.58) | CA12CA1CA2CA7CA9 | |
| SCHEMBL6882208 | 0.76 | CA12 (0.50) | CA12CA1CA2CA7CA9 | |
| Methyl 3-Hydroxybenzoate SCHEMBL67203 | 0.76 | P4HB (0.67) | CA12CA1CA2CA7CA9 | |
| Methyl 3-Hydroxybenzoate SCHEMBL29410714 | 0.76 | P4HB (0.67) | CA12CA1CA2CA7CA9 | |
| SCHEMBL10678343 | 0.75 | HSD17B1 (0.57) | CA12CA2CA9CA14LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6831106-B1 | Selective activity on cell proliferation and differentiation without displaying any hypercalcaemiant nature | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2004-12-14 | — | — | US | disclosed |