Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY2 | P41231 | 2/20 | 0.53 |
| ▸ | CASP3 | P42574 | 7/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 7/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 6/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 6/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6888217 | 0.84 | P2RY2 (0.53) | P2RY2CASP3SENP7SENP8SENP6 | |
| SCHEMBL6395255 | 0.82 | P2RY2 (0.62) | P2RY2SMN1; SMN2KDM4ENFKB1MAPT | |
| Phosphoric Acid SCHEMBL6393352 | 0.79 | P2RY2 (0.59) | P2RY2CASP3SENP7SENP8SENP6 | |
| Benzoic Acid SCHEMBL6395749 | 0.75 | P2RY2 (0.57) | P2RY2NPC1MAPT | |
| SCHEMBL6393348 | 0.75 | P2RY2 (0.82) | P2RY2CASP3SENP7SENP8SENP6 | |
| SCHEMBL334252 | 0.69 | NPC1 (0.61) | CASP3SENP7SENP8SENP6DYRK1A | |
| SCHEMBL30731280 | 0.69 | NPC1 (0.47) | P2RY2CASP3SENP7SENP8SENP6 | |
| SCHEMBL16655557 | 0.68 | NPC1 (0.43) | P2RY2CASP3SENP7SENP8SENP6 | |
| SCHEMBL30731277 | 0.67 | NPC1 (0.51) | CASP3SENP7SENP8SENP6DYRK1A | |
| SCHEMBL29040239 | 0.65 | CASP3 (0.41) | P2RY2CASP3SENP7SENP8SENP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1409503-A1 | NON-NATURAL CARBON-LINKED NUCLEOTIDES AND DINUCLEOTIDES | Celltech R & D Limited (GB) | 2004-04-21 | — | — | EP | disclosed |
| WO-2003011885-A1 | NON-NATURAL CARBON-LINKED NUCLEOTIDES AND DINUCLEOTIDES | CELLTECH R & D LIMITED (GB) | 2003-02-13 | — | — | WO | disclosed |