SCHEMBL6888282

SCHEMBL6888282

COC(=O)C=Cc1cn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)[nH]c1=O

nearest known ligand 0.70

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TK2 O00142 9/20 0.70
PYGM P11217 3/20 0.56
P2RY2 P41231 1/20 0.49
SLC28A1 O00337 1/20 0.48
SLC28A2 O43868 1/20 0.48
SLC29A1 Q99808 1/20 0.48
SLC28A3 Q9HAS3 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18573991 1.00 TK2 (0.70) TK2PYGMP2RY2SLC28A1SLC28A2
SCHEMBL14946349 1.00 TK2 (0.70) TK2PYGMP2RY2SLC28A1SLC28A2
SCHEMBL14916547 1.00 TK2 (0.70) TK2PYGMP2RY2SLC28A1SLC28A2
SCHEMBL6888284 1.00 TK2 (0.70) TK2PYGMP2RY2SLC28A1SLC28A2
SCHEMBL14929316 1.00 TK2 (0.70) TK2PYGMP2RY2SLC28A1SLC28A2
SCHEMBL2575473 1.00 TK2 (0.70) TK2PYGMP2RY2SLC28A1SLC28A2
Phosphoric Acid SCHEMBL21465238 0.96 TK2 (0.65) TK2PYGMP2RY2
SCHEMBL2582359 0.92 TK2 (0.61) TK2PYGM
SCHEMBL2582357 0.92 TK2 (0.61) TK2PYGM
SCHEMBL3071199 0.91 TK2 (0.58) TK2PYGM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1850 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260109727-A1 RNA CONSTRUCTS AND USES THEREOF BioNTech SE (DE) 2026-04-23 US claimed
EP-4634380-A1 INTERNAL RIBOSOME ENTRY SITES FOR IMPROVED POLYNUCLEOTIDE TRANSLATION ModernaTX, Inc. (US) 2025-10-22 EP claimed
US-20250295744-A1 TREATMENT INVOLVING NON-IMMUNOGENIC RNA FOR ANTIGEN VACCINATION AND PD-1 AXIS BINDING ANTAGONISTS BioNTech SE (DE) 2025-09-25 US claimed
US-20250277223-A1 METHODS OF TREATING OR PREVENTING AUTOIMMUNE DISEASES IMCYSE SA (BE) 2025-09-04 US claimed
EP-4598935-A2 RNA CONSTRUCTS AND USES THEREOF BioNTech SE (DE) 2025-08-13 EP claimed
WO-2025137275-A1 NOVEL CAS NUCLEASES AND POLYNUCLEOTIDES ENCODING THE SAME MODERNATX, INC. (US) 2025-06-26 WO claimed
EP-4565692-A2 INTERNAL RIBOSOME ENTRY SITES FOR IMPROVED POLYNUCLEOTIDE TRANSLATION ModernaTX, Inc. (US) 2025-06-11 EP claimed
US-20250161488-A1 THERAPEUTIC mRNA THE UNIVERSITY OF MELBOURNE (AU) 2025-05-22 US claimed
EP-4408886-A1 TREATMENT INVOLVING NON-IMMUNOGENIC RNA FOR ANTIGEN VACCINATION AND PD-1 AXIS BINDING ANTAGONISTS BioNTech SE (DE) 2024-08-07 EP claimed
WO-2024129779-A1 INTERNAL RIBOSOME ENTRY SITES FOR IMPROVED POLYNUCLEOTIDE TRANSLATION MODERNATX, INC. (US) 2024-06-20 WO claimed
WO-2023052531-A1 TREATMENT INVOLVING NON-IMMUNOGENIC RNA FOR ANTIGEN VACCINATION AND PD-1 AXIS BINDING ANTAGONISTS BioNTech SE (DE) 2023-04-06 WO claimed
EP-4126039-A1 TREATMENT INVOLVING NON-IMMUNOGENIC RNA FOR ANTIGEN VACCINATION BioNTech SE (DE) 2023-02-08 EP claimed
WO-2022248525-A1 METHODS OF TREATING OR PREVENTING AUTOIMMUNE DISEASES IMCYSE SA (BE) 2022-12-01 WO claimed
WO-2021198258-A1 TREATMENT INVOLVING NON-IMMUNOGENIC RNA FOR ANTIGEN VACCINATION BioNTech SE (DE) 2021-10-07 WO claimed
WO-2021197589-A1 TREATMENT INVOLVING NON-IMMUNOGENIC RNA FOR ANTIGEN VACCINATION BioNTech SE (DE) 2021-10-07 WO claimed
US-20200061166-A1 RNA FOR TREATMENT OF AUTOIMMUNE DISEASES BioNTech SE (DE) 2020-02-27 US claimed
EP-3609529-A1 RNA FOR TREATMENT OF AUTOIMMUNE DISEASES BioNTech RNA Pharmaceuticals GmbH (DE) 2020-02-19 EP claimed
CN-110719787-A RNA for treating autoimmune diseases 生物技术RNA制药有限公司 2020-01-21 CN claimed
WO-2018189193-A1 RNA FOR TREATMENT OF AUTOIMMUNE DISEASES BIONTECH RNA PHARMACEUTICALS GMBH (DE) 2018-10-18 WO claimed
WO-2018188730-A1 RNA FOR TREATMENT OF AUTOIMMUNE DISEASES BIONTECH RNA PHARMACEUTICALS GMBH (DE) 2018-10-18 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260109727-A1 RNA CONSTRUCTS AND USES THEREOF RNGTT, RNMT, NSUN3 TK2 1051/4885PYGM 689/4885P2RY2 577/4885
US-20250295744-A1 TREATMENT INVOLVING NON-IMMUNOGENIC RNA FOR ANTIGEN VACCINATION AND PD-1 AXIS BINDING ANTAGONISTS CD274, PDCD1LG2, PDCD1 TK2 2839/4885PYGM 2384/4885P2RY2 4405/4885
US-20200061166-A1 RNA FOR TREATMENT OF AUTOIMMUNE DISEASES NSUN3, RBM28, TRDMT1 TK2 2217/4885PYGM 4547/4885P2RY2 4335/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.