Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.52 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | PGK1 | P00558 | 3/20 | 0.38 |
| ▸ | PGK2 | P07205 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CPA1 | P15085 | 1/20 | 0.38 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.37 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | CPN1 | P15169 | 1/20 | 0.37 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3242802 | 0.82 | PTGS2 (0.54) | ALDH1A1TSHRCYP1A2MEN1KMT2A | |
| SCHEMBL2391075 | 0.82 | PTGS2 (0.54) | ALDH1A1TSHRCYP1A2MEN1KMT2A | |
| SCHEMBL10276277 | 0.82 | PTGS2 (0.54) | ALDH1A1TSHRCYP1A2MEN1KMT2A | |
| SCHEMBL28229032 | 0.81 | SRC (0.52) | SRCTSHRCYP1A2CYP2D6EPHX1 | |
| SCHEMBL583917 | 0.81 | AKR1B1 (0.52) | SRCALDH1A1TSHRCYP1A2CYSLTR2 | |
| SCHEMBL186896 | 0.80 | EPHX1 (0.51) | CYP1A2CPA1MEN1KMT2AEPHX1 | |
| SCHEMBL2891180 | 0.80 | AKR1C3 (0.47) | ALDH1A1CPN1CPB2 | |
| SCHEMBL27697908 | 0.76 | PTGS1 (0.40) | ALDH1A1PGK1PGK2CYP4F2CYP4A11 | |
| SCHEMBL5426254 | 0.76 | SRC (0.54) | SRCTRPA1ALDH1A1TSHRCES2 | |
| SCHEMBL2201031 | 0.76 | TRPA1 (0.48) | TRPA1ALDH1A1TSHRPGK1PGK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | disclosed |