Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TLR4 | O00206 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10357060 | 0.81 | PTGER4 (0.43) | MAPTMEN1KMT2AATMLMNA | |
| SCHEMBL11067298 | 0.80 | HTR1A (0.54) | HTR1AADRA1DADRA1AADRA1BMAPT | |
| SCHEMBL6458856 | 0.78 | MEN1 (0.48) | MAPTMEN1KMT2ACYP19A1CYP2C9 | |
| SCHEMBL6882078 | 0.77 | HPD (0.39) | PIN1MAPTMEN1KMT2ACYP19A1 | |
| SCHEMBL3952879 | 0.76 | ALDH1A1 (0.57) | HTR1AADRA1DADRA1AADRA1BMAPT | |
| SCHEMBL11451207 | 0.75 | MAPT (0.50) | HTR1AADRA1DADRA1AADRA1BPIN1 | |
| SCHEMBL16378450 | 0.75 | MAPT (0.39) | HTR1AADRA1DADRA1AADRA1BPIN1 | |
| SCHEMBL17746516 | 0.75 | MAPT (0.39) | HTR1AADRA1DADRA1AADRA1BPIN1 | |
| SCHEMBL5024079 | 0.74 | BACE1 (0.46) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL4290434 | 0.74 | POLB (0.55) | HTR1AADRA1DADRA1AADRA1BMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004110351-A2 | HETEROCYCLIC COMPOUNDS FOR TREATING HEPATITIS C VIRUS | ANADYS PHARMACEUTICALS, INC. (US) | 2004-12-23 | — | — | WO | disclosed |