Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 7/20 | 0.75 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.75 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.75 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.75 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.56 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.53 |
| ▸ | OR51E2 | Q9H255 | 2/20 | 0.53 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | KDM5C | P41229 | 2/20 | 0.53 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.53 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL6888987 | 1.00 | LMNA (0.75) | LMNAEGLN1ALKBH5SUCNR1GABRR1 | |
| Succinic Acid SCHEMBL27804789 | 0.87 | LMNA (0.82) | LMNAEGLN1ALKBH5SUCNR1GABRR1 | |
| Succinic Acid SCHEMBL1655131 | 0.87 | LMNA (0.82) | LMNAEGLN1ALKBH5SUCNR1GABRR1 | |
| Succinic Acid SCHEMBL28156291 | 0.87 | LMNA (0.82) | LMNAEGLN1ALKBH5SUCNR1GABRR1 | |
| Succinic Acid SCHEMBL28695489 | 0.87 | LMNA (0.82) | LMNAEGLN1ALKBH5SUCNR1GABRR1 | |
| Succinic Acid SCHEMBL7752977 | 0.87 | LMNA (0.82) | LMNAEGLN1ALKBH5SUCNR1GABRR1 | |
| Succinic Acid SCHEMBL28729193 | 0.87 | LMNA (0.82) | LMNAEGLN1ALKBH5SUCNR1GABRR1 | |
| Succinic Acid SCHEMBL1331200 | 0.87 | — | — | |
| Succinic Acid SCHEMBL24696 | 0.87 | LMNA (1.00) | LMNAEGLN1ALKBH5SUCNR1GABRR1 | |
| Succinic Acid SCHEMBL21867134 | 0.87 | LMNA (1.00) | LMNAEGLN1ALKBH5SUCNR1GABRR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6770607-B2 | CONTAINING ANIONIC SURFACTANT AND AMPHOTERIC SURFACTANT | UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. | 2004-08-03 | — | — | US | disclosed |
| WO-2004045576-A1 | VISCOELASTIC CLEANSING GEL WITH SURFACTANT SOLUTIONS CONTAINING POLYSACCHARIDES AND THEIR DERIVATIVE POLYSACCHARIDE HYDROCOLLOIDS | UNILEVER PLC (GB) | 2004-06-03 | — | — | WO | disclosed |
| US-20040097385-A1 | Viscoelastic cleansing gel with surfactant solutions containing polysaccharides and their derivatives polysaccharide hydrocolloids | UNILEVER HOME & PERSONAL PRODUCTS USA, DIVISION OF CONOPCO, INC. | 2004-05-20 | — | — | US | disclosed |
| WO-2004024101-A1 | VISCOELASTIC CLEANSING GEL WITH MICELLAR SURFACTANT SOLUTIONS | UNILEVER PLC (GB) | 2004-03-25 | — | — | WO | disclosed |
| US-20040053797-A1 | Viscoelastic cleansing gel with micellar surfactant solutions | UNILEVER HOME & PERSONAL PRODUCTS USA, DIVISION OF CONOPCO, INC. | 2004-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040097385-A1 | Viscoelastic cleansing gel with surfactant solutions containing polysaccharides and their derivatives polysaccharide hydrocolloids | CD44, ALG1, DDOST | SLC6A2 4801/4885LMNA 992/4885EGLN1 1399/4885 |
| US-20040053797-A1 | Viscoelastic cleansing gel with micellar surfactant solutions | BLM, POLG, RAD1 | SLC6A2 4814/4885LMNA 430/4885EGLN1 3727/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.