SCHEMBL6889160

SCHEMBL6889160

CCCc1ccc(CCc2ccc(-c3ccc(OCC)c(F)c3F)cc2F)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 7/20 0.43
GABRB2 P47870 7/20 0.43
ALOX5 P09917 2/20 0.38
NAAA Q02083 1/20 0.38
FGFR2 P21802 2/20 0.37
FGFR1 P11362 1/20 0.37
FFAR4 Q5NUL3 1/20 0.36
CTSL P07711 1/20 0.34
CTSS P25774 1/20 0.34
CTSK P43235 1/20 0.34
CALM1 P0DP23 1/20 0.34
NPC1 O15118 1/20 0.34
TP53 P04637 1/20 0.34
PKM P14618 1/20 0.34
RAB9A P51151 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
HSD17B10 Q99714 1/20 0.34
GABRA5 P31644 1/20 0.34
GABRA3 P34903 1/20 0.34
GABRA2 P47869 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8932329 0.95 NAAA (0.39) GABRA1GABRB2ALOX5NAAAFGFR2
SCHEMBL10301999 0.94 GABRA1 (0.42) GABRA1GABRB2ALOX5NAAAFGFR2
SCHEMBL22809285 0.91 GABRA1 (0.44) GABRA1GABRB2ALOX5NAAAFGFR2
SCHEMBL10302027 0.90 GABRA1 (0.43) GABRA1GABRB2ALOX5NAAAFGFR2
SCHEMBL17637058 0.88 GABRA1 (0.43) GABRA1GABRB2ALOX5NAAAFGFR2
SCHEMBL12740092 0.88 CTSL (0.41) GABRA1GABRB2ALOX5FGFR2FGFR1
SCHEMBL12735553 0.88 CTSL (0.41) GABRA1GABRB2ALOX5FGFR2FGFR1
SCHEMBL10302004 0.88 FFAR4 (0.38) GABRA1GABRB2NAAAFGFR2FGFR1
SCHEMBL12735642 0.87 NAAA (0.41) GABRA1GABRB2ALOX5NAAAFFAR4
SCHEMBL17946123 0.87 GABRA1 (0.41) GABRA1GABRB2ALOX5FGFR2FGFR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0945418-B1 LIQUID CRYSTAL COMPOUNDS EXHIBITING NEGATIVE ANISOTROPY OF PERMITTIVITY, LIQUID CRYSTAL COMPOSITIONS, AND LIQUID CRYSTAL DISPLAYS CHISSO CORP (JP) 2004-04-07 EP disclosed
US-6210761-B1 HIGH VOLTAGE HOLDING RATIO AND A LOW THRESHOLD VOLTAGE, ARE REMARKABLY SMALL IN THEIR DEPENDENCY ON TEMPERATURE, HARDLY EXHIBIT SMECTIC PHASE, AND ARE EXCELLENT IN MISCIBILITY WITH OTHER LIQUID CRYSTAL MATERIALS CHISSO CORPORATION (JP) 2001-04-03 US disclosed
EP-0945418-A1 LIQUID CRYSTAL COMPOUNDS EXHIBITING NEGATIVE ANISOTROPY OF PERMITTIVITY, LIQUID CRYSTAL COMPOSITIONS, AND LIQUID CRYSTAL DISPLAYS CHISSO CORPORATION (JP) 1999-09-29 EP disclosed