Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | NAMPT | P43490 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18459982 | 0.93 | L3MBTL1 (0.47) | L3MBTL1KMT2ASMN1; SMN2KDM4ENAMPT | |
| SCHEMBL20991495 | 0.93 | L3MBTL1 (0.47) | L3MBTL1KMT2ASMN1; SMN2KDM4ENAMPT | |
| SCHEMBL6437787 | 0.90 | L3MBTL1 (0.61) | L3MBTL1KMT2ASMN1; SMN2KDM4EPOLB | |
| SCHEMBL2588584 | 0.89 | SMN1; SMN2 (0.67) | L3MBTL1KMT2ASMN1; SMN2MEN1PTGS1 | |
| SCHEMBL10863404 | 0.86 | NAAA (0.61) | L3MBTL1KMT2ASMN1; SMN2ALDH1A1THRB | |
| SCHEMBL6536714 | 0.86 | NAAA (0.61) | L3MBTL1KMT2ASMN1; SMN2ALDH1A1THRB | |
| SCHEMBL2964483 | 0.86 | L3MBTL1 (0.69) | L3MBTL1KMT2ASMN1; SMN2KDM4ENAMPT | |
| SCHEMBL2977016 | 0.85 | KDM4E (0.65) | L3MBTL1KMT2AKDM4ENAMPTPOLB | |
| SCHEMBL15835231 | 0.84 | L3MBTL1 (0.56) | L3MBTL1KMT2ASMN1; SMN2KDM4EPOLB | |
| SCHEMBL2759013 | 0.82 | NTRK2 (0.56) | L3MBTL1KMT2ASMN1; SMN2KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2004502669-A | — | — | 2004-01-29 | — | — | JP | claimed |
| EP-1353898-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | Elan Pharmaceuticals, Inc. (US) | 2003-10-22 | — | — | EP | claimed |
| WO-2002002512-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2002-01-10 | — | — | WO | claimed |