Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | BLM | P54132 | 2/20 | 0.56 |
| ▸ | EGFR | P00533 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | RAD52 | P43351 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | NSD2 | O96028 | 2/20 | 0.51 |
| ▸ | FGB | P02675 | 1/20 | 0.51 |
| ▸ | MMP14 | P50281 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL6888365 | 0.89 | MAPT (0.60) | MEN1KMT2AMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL109325 | 0.88 | MEN1 (0.64) | MEN1KMT2AMAPTL3MBTL1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6577424 | 0.87 | MAPT (0.63) | MEN1KMT2AMAPTL3MBTL1ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL6665362 | 0.87 | MEN1 (0.50) | MEN1KMT2AMAPTL3MBTL1ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL6662164 | 0.85 | MEN1 (0.48) | MEN1KMT2AMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL8602072 | 0.84 | MAPT (0.63) | MEN1KMT2AMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL20334284 | 0.84 | NSD2 (0.63) | MEN1KMT2AMAPTL3MBTL1ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL6660175 | 0.83 | MAPT (0.49) | MEN1KMT2AMAPTL3MBTL1ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL6662414 | 0.83 | MAPT (0.49) | MEN1KMT2AMAPTL3MBTL1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8603274 | 0.83 | MAPT (0.61) | MEN1KMT2AMAPTL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040248765-A1 | Tumour targeting prodrugs activated by metallo matrixproteinases | COURT OF NAPIER UNIVERSITY, THE (GB) | 2004-12-09 | — | — | US | disclosed |
| EP-1366064-A1 | TUMOUR TARGETING PRODRUGS ACTIVATED BY METALLO MATRIXPROTEINASES | The Court of Napier University (GB) | 2003-12-03 | — | — | EP | disclosed |
| WO-2002072620-A1 | TUMOUR TARGETING PRODRUGS ACTIVATED BY METALLO MATRIXPROTEINASES | THE COURT OF NAPIER UNIVERSITY (GB) | 2002-09-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040248765-A1 | Tumour targeting prodrugs activated by metallo matrixproteinases | MMP2, MMP26, ADAM17 | MEN1 223/4885KMT2A 1487/4885MAPT 4871/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.