Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | ESRRG | P62508 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21335533 | 0.98 | MAPT (0.49) | MAPTALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL3079822 | 0.85 | CNR1 (0.38) | ALDH1A1POLBCNR1CNR2 | |
| SCHEMBL1879427 | 0.82 | HDAC3 (0.56) | MAPTALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL5940572 | 0.82 | HTT (0.52) | MAPTALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL1877455 | 0.81 | EPHX2 (0.48) | EPHX2HDAC3HDAC1HDAC2MEN1 | |
| SCHEMBL689307 | 0.80 | HDAC3 (0.58) | MAPTALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL11074386 | 0.79 | NPC1 (0.52) | MAPTALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL4023884 | 0.79 | PHLPP2 (0.48) | MAPTALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL22266817 | 0.78 | HDAC1 (0.44) | MAPTALDH1A1LMNAHDAC3HDAC1 | |
| SCHEMBL20180466 | 0.78 | EPHX2 (0.49) | MAPTALDH1A1NPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170135933-A1 | PHOTOPROTECTIVE COMPOSITIONS COMPRISING PHOTOSENSITIVE 1,3,5-TRIAZINE COMPOUNDS, DIBENZOYLMETHANE COMPOUNDS AND SILICEOUS S-TRIAZINES SUBSTITUTED WITH TWO AMINOBENZOATE OR AMINOBENZAMIDE GROUPS | L'OREAL (FR) | 2017-05-18 | — | — | US | disclosed |
| US-8999299-B2 | Photoprotective cosmetic compositions comprising silicon-containing s-triazine compounds substituted with two aminobenzoate or aminobenzamide groups and non-silicon-containing lipophilic triazine compound UV-screening agents | L'OREAL (FR) | 2015-04-07 | — | — | US | disclosed |
| US-8747816-B2 | UV-photoprotective compositions comprising diebenzoylmethane screening agents and silicon-containing s-triazine compounds substituted with two aminobenzoate or aminobenzamide groups | L'OREAL (FR) | 2014-06-10 | — | — | US | disclosed |
| US-20130012373-A1 | S-TRIAZINE SUNSCREENS BEARING HINDERED PARA-AMINOBENZALMALONATE/PARA-AMINOBENZALMALONAMIDE AND AMINOBENZOATE/AMINOBENZAMIDE SUBSTITUENTS | L'OREAL (FR) | 2013-01-10 | — | — | US | disclosed |
| US-8323624-B2 | S-triazine sunscreens bearing hindered para-aminobenzalmalonate/para-aminobenzalmalonamide and aminobenzoate/aminobenzamide substituents | L'OREAL (FR) | 2012-12-04 | — | — | US | disclosed |
| EP-1927343-B1 | Photoprotective composition containing a photosensitive 1,3,5-triazine derivative, a dibenzoylmethane derivative and a siliceous s-triazine substituted with two aminobenzoate or aminobenzamide groups | OREAL (FR) | 2012-02-29 | — | — | EP | disclosed |
| EP-1927345-B1 | Cosmetic composition containing the combination of a silicon-containing s-triazine substituted with two aminobenzoate or aminobenzamide groups and a silicon-free lipophilic triazine UV-screening agent | OREAL (FR) | 2012-01-18 | — | — | EP | disclosed |
| EP-1642893-B1 | s-triazine compounds possessing two substituents selected from bulky para-aminobenzalmalonate and para-aminobenzalmalonamide groups and one aminobenzoate substituent, compositions and uses thereof | OREAL (FR) | 2011-05-25 | — | — | EP | disclosed |
| EP-1891079-B1 | PHOTOSTABILIZATION OF A DIBENZOYLMETHANE BY A SILICON- CONTAINING S-TRIAZINE SUBSTITUTED WITH TWO AMINOBENZOATE OR AMINOBENZAMIDE GROUPS; PHOTOPROTECTIVE COMPOSITIONS. NOVEL SILICON-CONTAINING S-TRIAZINE COMPOUNDS | OREAL (FR) | 2010-10-27 | — | — | EP | disclosed |
| US-20100003207-A1 | Photoprotective compositions comprising photosensitive 1,3,5-triazine compounds, dibenzoylmethane compounds and siliceous s-triazines substituted with two aminobenzoate or aminobenzamide groups | L'OREAL (FR) | 2010-01-07 | — | — | US | disclosed |
| EP-1891079-A1 | PHOTOSTABILIZATION OF A DIBENZOYLMETHANE BY A SILICON- CONTAINING S-TRIAZINE SUBSTITUTED WITH TWO AMINOBENZOATE OR AMINOBENZAMIDE GROUPS; PHOTOPROTECTIVE COMPOSITIONS. NOVEL SILICON-CONTAINING S-TRIAZINE COMPOUNDS | L'Oréal (FR) | 2008-02-27 | — | — | EP | disclosed |
| US-20080008669-A1 | Photostable sunscreen compositions comprising cinnamate ester UV-B filters and s-triazine compounds | L'OREAL (FR) | 2008-01-10 | — | — | US | disclosed |
| US-20070218022-A1 | Photostable sunscreen compositions comprising cinnamic acid ester UV-B filters, dibenzoylmethane UV-A filters and s-triazine compounds | L'OREAL, PARIS, FRANCE | 2007-09-20 | — | — | US | disclosed |
| US-20070196294-A1 | Photostable sunscreen compositions comprising dibenzoylmethane compound UV-A filters and s-triazine compounds | L'OREAL (FR) | 2007-08-23 | — | — | US | disclosed |
| EP-1815885-A2 | Compositions containing a UV-B filter of the cinnamic acid ester type and a s-triazine derivative; process of photostabilising a UV-B filter of the cinnamic acid ester type | L'Oréal (FR) | 2007-08-08 | — | — | EP | disclosed |
| EP-1815884-A2 | Compositions containing an UV-B filter of the cinnamic acid ester type, a UV-A filter of the dibenzoylmethane type and a derivative of s-triazine; process of photostabilisation | L'Oréal (FR) | 2007-08-08 | — | — | EP | disclosed |
| EP-1815886-A2 | Compositions containing a UV-A filter of the dibenzoylmethane type and a s-triazine derivative; process of photostabilisation | L'Oréal (FR) | 2007-08-08 | — | — | EP | disclosed |
| WO-2006128732-A1 | PHOTOSTABILIZATION OF A DIBENZOYLMETHANE BY A SILICON- CONTAINING S-TRIAZINE SUBSTITUTED WITH TWO AMINOBENZOATE OR AMINOBENZAMIDE GROUPS; PHOTOPROTECTIVE COMPOSITIONS. NOVEL SILICON-CONTAINING S-TRIAZINE COMPOUNDS | L'OREAL (FR) | 2006-12-07 | — | — | WO | disclosed |
| EP-1642893-A1 | s-triazine compounds possessing two substituents selected from bulky para-aminobenzalmalonate and para-aminobenzalmalonamide groups and one aminobenzoate substituent, compositions and uses thereof | L'OREAL (FR) | 2006-04-05 | — | — | EP | disclosed |
| US-20060045859-A1 | S-triazine sunscreens bearing hindered para-aminobenzalmalonate/para-aminobenzalmalonamide and aminobenzoate/aminobenzamide substituents | L'OREAL (FR) | 2006-03-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070218022-A1 | Photostable sunscreen compositions comprising cinnamic acid ester UV-B filters, dibenzoylmethane UV-A filters and s-triazine compounds | NISCH, SUN2, CDC73 | MAPT 1002/4885ALDH1A1 928/4885NPC1 1465/4885 |
| US-20060045859-A1 | S-triazine sunscreens bearing hindered para-aminobenzalmalonate/para-aminobenzalmalonamide and aminobenzoate/aminobenzamide substituents | TYR, ARSA, TST | MAPT 878/4885ALDH1A1 623/4885NPC1 4471/4885 |
| US-20100003207-A1 | Photoprotective compositions comprising photosensitive 1,3,5-triazine compounds, dibenzoylmethane compounds and siliceous s-triazines substituted with two aminobenzoate or aminobenzamide groups | CUTA, TST, DSG1 | MAPT 36/4885ALDH1A1 3175/4885NPC1 4373/4885 |
| US-20130012373-A1 | S-TRIAZINE SUNSCREENS BEARING HINDERED PARA-AMINOBENZALMALONATE/PARA-AMINOBENZALMALONAMIDE AND AMINOBENZOATE/AMINOBENZAMIDE SUBSTITUENTS | TYR, ARSA, TST | MAPT 878/4885ALDH1A1 623/4885NPC1 4471/4885 |
| US-20080008669-A1 | Photostable sunscreen compositions comprising cinnamate ester UV-B filters and s-triazine compounds | NISCH, SUN2, ERCC5 | MAPT 724/4885ALDH1A1 1094/4885NPC1 1292/4885 |
| US-20070196294-A1 | Photostable sunscreen compositions comprising dibenzoylmethane compound UV-A filters and s-triazine compounds | SUN2, ERCC5, NISCH | MAPT 263/4885ALDH1A1 1312/4885NPC1 2756/4885 |
| US-20170135933-A1 | PHOTOPROTECTIVE COMPOSITIONS COMPRISING PHOTOSENSITIVE 1,3,5-TRIAZINE COMPOUNDS, DIBENZOYLMETHANE COMPOUNDS AND SILICEOUS S-TRIAZINES SUBSTITUTED WITH TWO AMINOBENZOATE OR AMINOBENZAMIDE GROUPS | CUTA, TST, DSG1 | MAPT 36/4885ALDH1A1 3175/4885NPC1 4373/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.