Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CPT2 | P23786 | 1/20 | 0.33 |
| ▸ | ACLY | P53396 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL988316 | 0.98 | PDE4A (0.41) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| SCHEMBL5173599 | 0.91 | TDP1 (0.43) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| SCHEMBL388741 | 0.86 | HSPD1 (0.33) | PDE4ALMNAUSP2SLCO1B1 | |
| SCHEMBL28139281 | 0.85 | USP2 (0.37) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| SCHEMBL30970938 | 0.82 | PDE4A (0.43) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| SCHEMBL25394043 | 0.81 | LMNA (0.36) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| SCHEMBL3862940 | 0.80 | LMNA (0.40) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| SCHEMBL4727419 | 0.80 | LMNA (0.44) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| SCHEMBL18103757 | 0.80 | LMNA (0.40) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| Potassium Ion SCHEMBL9419063 | 0.80 | LMNA (0.40) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6812298-B2 | HIGHLY BRANCHED, THERMOPLASTIC POLYMERS HAVING LOWER VISCOSITY AND BETTER SHEAR THINNING PROPERTIES FOR COATING USES THAN A CHEMICALLY SIMILAR LINEAR POLYMER HAVING THE SAME MOLECULAR WEIGHT AND SAME CONCENTRATION; GELATION INHIBITION | MICHIGAN MOLECULAR INSTITUTE | 2004-11-02 | — | — | US | disclosed |
| US-20030069370-A1 | Hyperbranched polyureas, polyurethanes, polyamidoamines, polyamides and polyesters | DVORNIC PETAR R (US) | 2003-04-10 | — | — | US | disclosed |
| US-6534600-B2 | Interpenetrating polymer network | MICHIGAN MOLECULAR INSTITUTE | 2003-03-18 | — | — | US | disclosed |
| US-20020161113-A1 | Hyperbranched polyureas, polyurethanes, polyamidoamines, polyamides and polyesters | 3M INNOVATIVE PROPERTIES COMPANY | 2002-10-31 | — | — | US | disclosed |