Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPD1 | P10809 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.31 |
| ▸ | SPTLC1 | O15269 | 1/20 | 0.31 |
| ▸ | SPTLC2 | O15270 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL988316 | 0.87 | PDE4A (0.41) | HSPD1BLMHSPE1PDE4ALMNA | |
| SCHEMBL6889487 | 0.86 | PDE4A (0.39) | PDE4ALMNAUSP2SLCO1B1 | |
| SCHEMBL5173599 | 0.81 | TDP1 (0.43) | PDE4ALMNAUSP2SLCO1B1 | |
| SCHEMBL27666368 | 0.80 | HSPD1 (0.39) | HSPD1BLMHSPE1PDE4ASPTLC1 | |
| SCHEMBL27871272 | 0.79 | HSPD1 (0.41) | HSPD1BLMHSPE1SPTLC1SPTLC2 | |
| SCHEMBL28139281 | 0.76 | USP2 (0.37) | PDE4ALMNAUSP2SLCO1B1 | |
| SCHEMBL30970938 | 0.73 | PDE4A (0.43) | PDE4ALMNAUSP2SLCO1B1 | |
| SCHEMBL25394043 | 0.73 | LMNA (0.36) | PDE4ALMNAUSP2SLCO1B1 | |
| SCHEMBL5161849 | 0.72 | PDE4A (0.63) | PDE4ALMNAUSP2SLCO1B1 | |
| SCHEMBL9577669 | 0.71 | LMNA (0.33) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2333001-B1 | COMPOSITIONS OF POLYESTERS WITH A HIGH GLASS TRANSITION TEMPERATURE WHICH COMPRISE 2,2,4,4-TETRAMETHYL-1,3-CYCLOBUTANEDIOL AND CERTAIN THERMAL STABILIZERS AND ARTICLES THEREOF | EASTMAN CHEM CO (US) | 2018-07-25 | — | — | EP | disclosed |
| US-10017606-B2 | Polyester compositions containing cyclobutanediol having a certain combination of inherent viscosity and moderate glass transition temperature and articles made therefrom | EASTMAN CHEMICAL COMPANY (US) | 2018-07-10 | — | — | US | disclosed |
| US-9765203-B2 | Polyester compositions which comprise cyclobutanediol and certain thermal stabilizers, and/or reaction products thereof | EASTMAN CHEMICAL COMPANY (US) | 2017-09-19 | — | — | US | disclosed |
| US-20170174828-A1 | POLYESTER COMPOSITIONS CONTAINING CYCLOBUTANEDIOL HAVING A CERTAIN COMBINATION OF INHERENT VISCOSITY AND MODERATE GLASS TRANSITION TEMPERATURE AND ARTICLES MADE THEREFROM | EASTMAN CHEMICAL COMPANY (US) | 2017-06-22 | — | — | US | disclosed |
| US-9598533-B2 | Polyester compositions containing cyclobutanediol having a certain combination of inherent viscosity and moderate glass transition temperature and articles made therefrom | EASTMAN CHEMICAL COMPANY (US) | 2017-03-21 | — | — | US | disclosed |
| US-20160017125-A1 | POLYESTER COMPOSITIONS WHICH COMPRISE CYCLOBUTANEDIOL AND CERTAIN THERMAL STABILIZERS, AND/OR REACTION PRODUCTS THEREOF | EASTMAN CHEMICAL COMPANY (US) | 2016-01-21 | — | — | US | disclosed |
| US-9169388-B2 | Polyester compositions which comprise cyclobutanediol and certain thermal stabilizers, and/or reaction products thereof | EASTMAN CHEMICAL COMPANY (US) | 2015-10-27 | — | — | US | disclosed |
| EP-2332592-B1 | Polyester compositions containing 2,2,4,4-tetramethyl-1,3-cyclobutanediol having a particular combination of inherent viscosity and moderate glass transition temperature and articles therefrom | EASTMAN CHEM CO (US) | 2015-09-09 | — | — | EP | disclosed |
| US-20130303692-A1 | POLYESTER COMPOSITIONS CONTAINING CYCLOBUTANEDIOL HAVING A CERTAIN COMBINATION OF INHERENT VISCOSITY AND MODERATE GLASS TRANSITION TEMPERATURE AND ARTICLES MADE THEREFROM | EASTMAN CHEMICAL COMPANY | 2013-11-14 | — | — | US | disclosed |
| US-8507638-B2 | Polyester compositions containing cyclobutanediol having a certain combination of inherent viscosity and moderate glass transition temperature and articles made therefrom | EASTMAN CHEMICAL COMPANY (US) | 2013-08-13 | — | — | US | disclosed |
| WO-2007123631-A1 | POLYESTER COMPOSITIONS WHICH COMPRISE CYCLOBUTANEDIOL AND AT LEAST ONE PHOSPHORUS COMPOUND | EASTMAN CHEMICAL COMPANY (US) | 2007-11-01 | — | — | WO | disclosed |
| US-20070129531-A1 | Polyester compositions which comprise cyclobutanediol and certain phosphate thermal stabilizers, and/or reaction products thereof | EASTMAN CHEMICAL COMPANY | 2007-06-07 | — | — | US | disclosed |
| US-20070105993-A1 | Polyester compositions which comprise cyclobutanediol and at least one phosphorus compound | EASTMAN CHEMICAL COMPANY | 2007-05-10 | — | — | US | disclosed |
| WO-2007053549-A1 | POLYESTER COMPOSITIONS CONTAINING CYCLOBUTANEDIOL HAVING A CERTAIN COMBINATION OF INHERENT VISCOSITY AND MODERATE GLASS TRANSITION TEMPERATURE AND ARTICLES MADE THEREFROM | EASTMAN CHEMICAL COMPANY (US) | 2007-05-10 | — | — | WO | disclosed |
| WO-2007053548-A2 | POLYESTER COMPOSITIONS COMPRISING MINIMAL AMOUNTS OF CYCLOBUTANEDIOL | EASTMAN CHEMICAL COMPANY (US) | 2007-05-10 | — | — | WO | disclosed |
| WO-2007053460-A1 | POLYESTER COMPOSITIONS WHICH COMPRISE CYCLOBUTANEDIOL AND AT LEAST ONE PHOSPHORUS COMPOUND | EASTMAN CHEMICAL COMPANY (US) | 2007-05-10 | — | — | WO | disclosed |
| US-20070106054-A1 | Polyester compositions containing cyclobutanediol having a certain combination of inherent viscosity and high glass transition temperature and articles made therefrom | EASTMAN CHEMICAL COMPANY | 2007-05-10 | — | — | US | disclosed |
| WO-2007053550-A1 | POLYESTER COMPOSITIONS CONTAINING CYCLOBUTANEDIOL HAVING HIGH GLASS TRANSITION TEMPERATURE AND ARTICLES MADE THEREFROM | EASTMAN CHEMICAL COMPANY (US) | 2007-05-10 | — | — | WO | disclosed |
| WO-2007053434-A1 | POLYESTER COMPOSITIONS WHICH COMPRISE CYCLOBUTANEDIOL AND CERTAIN THERMAL STABILIZERS, AND/OR REACTION PRODUCTS THEREOF | EASTMAN CHEMICAL COMPANY (US) | 2007-05-10 | — | — | WO | disclosed |
| US-20070100122-A1 | Polyester compositions containing cyclobutanediol and articles made therefrom | EASTMAN CHEMICAL COMPANY | 2007-05-03 | — | — | US | disclosed |