Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.58 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20576435 | 0.85 | MEN1 (0.44) | MEN1KMT2ATAAR1FOLH1EPHX1 | |
| SCHEMBL8763940 | 0.83 | TAAR1 (0.69) | MEN1KMT2ATAAR1EPHX1HTT | |
| SCHEMBL4333892 | 0.81 | NPC1 (0.49) | MEN1KMT2ATAAR1FOLH1CLCN2 | |
| SCHEMBL157592 | 0.78 | FOLH1 (0.53) | MEN1KMT2AFOLH1CLCN2TSHR | |
| SCHEMBL6094753 | 0.77 | FOLH1 (0.42) | MEN1KMT2ATAAR1FOLH1EPHX1 | |
| SCHEMBL17799517 | 0.76 | FOLH1 (0.52) | MEN1KMT2AFOLH1CLCN2TSHR | |
| SCHEMBL264745 | 0.75 | FOLH1 (0.50) | TAAR1FOLH1CLCN2TSHRALDH1A1 | |
| SCHEMBL11141533 | 0.75 | FOLH1 (0.50) | TAAR1FOLH1CLCN2TSHRALDH1A1 | |
| SCHEMBL6839201 | 0.75 | FOLH1 (0.50) | TAAR1FOLH1CLCN2TSHRALDH1A1 | |
| SCHEMBL9459072 | 0.75 | ESR1 (0.60) | MEN1KMT2ATAAR1FOLH1CLCN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040082079-A1 | Low affinity screening method | GRAFFINITY PHARMACEUTICALS AG. (DE) | 2004-04-29 | — | — | US | disclosed |
| EP-1360489-A1 | LOW AFFINITY SCREENING METHOD | Graffinity Pharmaceuticals Aktiengesellschaft (DE) | 2003-11-12 | — | — | EP | disclosed |
| WO-2002063299-A1 | LOW AFFINITY SCREENING METHOD | GRAFFINITY PHARMACEUTICALS AG (DE) | 2002-08-15 | — | — | WO | disclosed |