Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 5/20 | 0.35 |
| ▸ | LAP3 | P28838 | 4/20 | 0.35 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.35 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19211983 | 0.72 | FDPS (0.31) | — | |
| SCHEMBL2460208 | 0.72 | FDPS (0.31) | — | |
| SCHEMBL9630675 | 0.72 | LAP3 (0.33) | ANPEPLAP3ERAP2ERAP1 | |
| SCHEMBL28416439 | 0.70 | — | — | |
| SCHEMBL17880776 | 0.67 | — | — | |
| SCHEMBL442716 | 0.67 | — | — | |
| SCHEMBL17880777 | 0.67 | — | — | |
| SCHEMBL9307779 | 0.66 | GABRR1 (0.35) | — | |
| SCHEMBL9307785 | 0.66 | GABRR1 (0.35) | — | |
| SCHEMBL439474 | 0.65 | CA2 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040241173-A1 | Formed via hydrolysis; antibiotic resistance; may contain penicillins, cephalosporins, quinolones, fluoroquinolones, macrolides, lincosamines, carbepenems, conobactams, aminoglycosides, glycopeptides, tetracyclines, sulfonamides, rifampin, oxazolidonones, and streptogramins | WILLIAM MARSH RICE UNIVERSITY (US) | 2004-12-02 | — | — | US | disclosed |