SCHEMBL6890135

SCHEMBL6890135

CCCCCCC(CCC(CCC(CCCCC)C(=O)O)C(=O)O)C(=O)O

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 2/20 0.66
GRIK2 Q13002 2/20 0.66
CA2 P00918 2/20 0.64
MAPK1 P28482 1/20 0.64
SLC1A2 P43004 2/20 0.62
SLC1A1 P43005 2/20 0.62
GPR84 Q9NQS5 7/20 0.61
FFAR1 O14842 1/20 0.61
CHRM1 P11229 1/20 0.61
AKR1A1 P14550 1/20 0.61
CHRM3 P20309 1/20 0.61
HTR2A P28223 1/20 0.61
HTR2C P28335 1/20 0.61
ADRA1A P35348 1/20 0.61
HRH1 P35367 1/20 0.61
DRD3 P35462 1/20 0.61
SLC6A3 Q01959 1/20 0.61
HDAC1 Q13547 1/20 0.61
HDAC2 Q92769 1/20 0.61
TDP1 Q9NUW8 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL285336 1.00 GRIK1 (0.66) GRIK1GRIK2CA2MAPK1SLC1A2
SCHEMBL1197355 1.00 GRIK1 (0.66) GRIK1GRIK2CA2MAPK1SLC1A2
SCHEMBL542365 1.00 GRIK1 (0.66) GRIK1GRIK2CA2MAPK1SLC1A2
SCHEMBL487044 1.00 GRIK1 (0.66) GRIK1GRIK2CA2MAPK1SLC1A2
SCHEMBL1117936 1.00 GRIK1 (0.66) GRIK1GRIK2CA2MAPK1SLC1A2
SCHEMBL5594553 1.00 GRIK1 (0.66) GRIK1GRIK2CA2MAPK1SLC1A2
SCHEMBL4406612 1.00 GRIK1 (0.66) GRIK1GRIK2CA2MAPK1SLC1A2
SCHEMBL906020 0.98 CA2 (0.68) GRIK1GRIK2CA2MAPK1SLC1A2
Ammonia Solution, Strong SCHEMBL22729209 0.98 GRIK1 (0.63) GRIK1GRIK2CA2MAPK1SLC1A2
SCHEMBL25286591 0.98 GRIK1 (0.68) GRIK1GRIK2CA2MAPK1SLC1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140099354-A1 BIOPASSIVATING MEMBRANE STABILIZATION BY MEANS OF NITROCARBOXYLIC ACID-CONTAINING PHOSPHOLIPIDS IN PREPARATIONS AND COATINGS Dietz, Ulrich (DE) 2014-04-10 US disclosed
US-20040115233-A1 Composition for improving skin environment and clothes thereof FUKUMOTO KATSUMORI (JP) 2004-06-17 US disclosed
US-4673684-A Amide derivatives and 5-lipoxygenase inhibitors containing the same as an active ingredient TERUMO CORPORATION (JP) 1987-06-16 US disclosed
US-4619938-A Fatty acid derivatives of aminoalkyl nicotinic acid esters and platelet aggregation inhibitors TERUMO KABUSHIKI KAISHA (JP) 1986-10-28 US disclosed
EP-0161422-A1 Alkanolamine derivatives and platelet aggregation inhibitors containing the same as an active ingredient TERUMO KABUSHIKI KAISHA trading as TERUMO CORPORATION (JP) 1985-11-21 EP disclosed
EP-0157420-A2 Amide derivatives and 5-lipoxygenase inhibitors containing the same as an active ingredient TERUMO KABUSHIKI KAISHA trading as TERUMO CORPORATION (JP) 1985-10-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140099354-A1 BIOPASSIVATING MEMBRANE STABILIZATION BY MEANS OF NITROCARBOXYLIC ACID-CONTAINING PHOSPHOLIPIDS IN PREPARATIONS AND COATINGS PHOSPHO1, PTDSS1, LIPG GRIK1 3572/4885GRIK2 3884/4885CA2 1812/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.