Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 4/20 | 0.52 |
| ▸ | DRD2 | P14416 | 3/20 | 0.48 |
| ▸ | DRD3 | P35462 | 3/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.48 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4754349 | 0.88 | DRD4 (0.55) | DRD4DRD2DRD3KCNH2ALDH3A1 | |
| SCHEMBL14832975 | 0.88 | DRD4 (0.44) | DRD4DRD2DRD3KCNH2ALDH3A1 | |
| SCHEMBL8140756 | 0.87 | NPC1 (0.47) | NPC1RAB9ASMN1; SMN2LTA4H | |
| SCHEMBL1172364 | 0.86 | DRD4 (0.53) | DRD4DRD2DRD3KCNH2ALDH3A1 | |
| SCHEMBL1345118 | 0.85 | MAOB (0.57) | DRD4DRD2DRD3KCNH2ALDH3A1 | |
| SCHEMBL7621718 | 0.85 | HRH3 (0.53) | DRD4DRD2DRD3KCNH2ALDH3A1 | |
| SCHEMBL10384122 | 0.85 | HRH3 (0.53) | DRD4DRD2DRD3KCNH2ALDH3A1 | |
| SCHEMBL6752147 | 0.85 | HRH3 (0.53) | DRD4DRD2DRD3KCNH2ALDH3A1 | |
| SCHEMBL7390013 | 0.85 | HRH3 (0.53) | DRD4DRD2DRD3KCNH2ALDH3A1 | |
| SCHEMBL10732157 | 0.83 | LTA4H (0.53) | DRD4DRD2DRD3KCNH2ALDH3A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 279 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117105872-B | Benzodiazepine compound and preparation method and application thereof | 徐州医科大学 | 2024-10-15 | — | — | CN | claimed |
| CN-117105872-A | Benzodiazepine compound and preparation method and application thereof | 徐州医科大学 | 2023-11-24 | — | — | CN | claimed |
| EP-1420021-A1 | DNA Methyltransferase inhibitors | The Penn State Research Foundation (US) | 2004-05-19 | — | — | EP | claimed |
| JP-2003501431-A | — | — | 2003-01-14 | — | — | JP | claimed |
| EP-1181291-A2 | DNA METHYLTRANSFERASE INHIBITORS | THE PENN STATE RESEARCH FOUNDATION (US) | 2002-02-27 | — | — | EP | claimed |
| WO-2000075142-A2 | DNA METHYLTRANSFERASE INHIBITORS | THE PENN STATE RESEARCH FOUNDATION (US) | 2000-12-14 | — | — | WO | claimed |
| US-4554356-A | Method for production of imidazolyl vinyl ethers | SIEGFRIED AKTIENGESELLSCHAFT (CH) | 1985-11-19 | — | — | US | claimed |
| EP-3233077-B1 | DOPAMINE D2 RECEPTOR LIGANDS | BROAD INST INC (US) | 2026-05-06 | — | — | EP | disclosed |
| US-12428373-B2 | Dopamine D2 receptor ligands | THE BROAD INSTITUTE, INC. (US) | 2025-09-30 | — | — | US | disclosed |
| WO-2025024563-A2 | CAP ANALOGS AND METHODS OF USE THEREOF | TRILINK BIOTECHNOLOGIES, LLC (US) | 2025-01-30 | — | — | WO | disclosed |
| CN-117105872-B | Benzodiazepine compound and preparation method and application thereof | 徐州医科大学 | 2024-10-15 | — | — | CN | disclosed |
| US-20240189304-A1 | BET PROTEIN INHIBITORS AND USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-06-13 | — | — | US | disclosed |
| CN-118164914-A | Indazole compound and synthetic method and application thereof | 华东师范大学 | 2024-06-11 | — | — | CN | disclosed |
| EP-0034894-A2 | 2-(1-Piperazinyl)-2,4,6-cycloheptatrien-1-one derivatives, processes for their preparation, intermediates used in the processes and the preparation thereof and pharmaceutical compositions containing the derivatives | AYERST, MCKENNA AND HARRISON INC. (CA) | 1981-09-02 | — | — | EP | disclosed |
| US-4268507-A | Monophosphonate compounds as hypoglycemic and/or antiartherogenic agents | SYMPHAR S.A. (CH) | 1981-05-19 | — | — | US | disclosed |
| EP-0016310-A1 | Monophosphonate compounds, process for their preparation and pharmaceutical compositions containing them | SYMPHAR S.A. (CH) | 1980-10-01 | — | — | EP | disclosed |
| US-4210657-A | FUNGICIDES, BACTERICIDES | SIEGFRIED AKTIENGESELLSCHAFT (CH) | 1980-07-01 | — | — | US | disclosed |
| EP-0008804-A1 | Imidazolylvinylethers, their preparation and application as active agent in pharmaceutical and biocidal compositions | SIEGFRIED AKTIENGESELLSCHAFT (CH) | 1980-03-19 | — | — | EP | disclosed |
| US-4017631-A | MICROBIOCIDES | JANSSEN PHARMACEUTICA N.V. (BE) | 1977-04-12 | — | — | US | disclosed |
| US-3991202-A | ANTIMICROBIALS | JANSSEN PHARMACEUTICA N.V. (BE) | 1976-11-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12428373-B2 | Dopamine D2 receptor ligands | DRD2, SLC6A3, NTSR2 | DRD4 12/4885DRD2 1/4885DRD3 4/4885 |
| US-20240189304-A1 | BET PROTEIN INHIBITORS AND USE THEREOF | BET1, BRD4, BRPF3 | DRD4 4349/4885DRD2 4194/4885DRD3 4090/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.