Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.53 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | CCR3 | P51677 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | GRM5 | P41594 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10059196 | 0.82 | HCAR3 (0.49) | ALDH1A1MEN1KMT2AGLAOPRM1 | |
| SCHEMBL4673529 | 0.82 | HCAR3 (0.49) | ALDH1A1MEN1KMT2AUSP2NPSR1 | |
| SCHEMBL2544136 | 0.82 | LMNA (0.56) | ALDH1A1HTTUSP2NPSR1TSHR | |
| Hydrochloric Acid SCHEMBL5857416 | 0.81 | LMNA (0.55) | ALDH1A1HTTUSP2NPSR1TSHR | |
| SCHEMBL3137899 | 0.79 | HCAR3 (0.49) | ALDH1A1MEN1KMT2AGLANPSR1 | |
| SCHEMBL829129 | 0.78 | USP2 (0.52) | ALDH1A1MEN1KMT2AGLAHTT | |
| Hydrochloric Acid SCHEMBL29769997 | 0.78 | SMN1; SMN2 (0.48) | ALDH1A1NPSR1TSHRLMNAPKM | |
| Hydrochloric Acid SCHEMBL26907902 | 0.78 | SMN1; SMN2 (0.48) | ALDH1A1NPSR1TSHRLMNAPKM | |
| Hydrochloric Acid SCHEMBL829074 | 0.77 | USP2 (0.51) | ALDH1A1MEN1KMT2AGLAHTT | |
| SCHEMBL4752964 | 0.75 | CCR3 (0.51) | ALDH1A1KMT2AKDM4EUSP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6806275-B2 | PSYCHOLOGICAL DISORDERS; SIDE EFFECT REDUCTION | NIHON NOHYAKU CO., LTD. (JP) | 2004-10-19 | — | — | US | disclosed |
| CN-1166665-C | Arylpiperidine derivatives and use thereof | �ձ��ݶ�ũҩ��ʽ���� | 2004-09-15 | — | — | CN | disclosed |
| US-20020156283-A1 | Arylpiperidine derivatives and use thereof | NIHON NOHYAKU CO., LTD. (JP) | 2002-10-24 | — | — | US | disclosed |
| US-6407121-B1 | DOPAMINE D4 RECEPTOR ANTAGONISTS; PSYCHOLOGICAL AND BRAIN DISORDERS; ALZHEIMER*S DISEASE, SCHIZOPHRENIA; SIDE EFFECT REDUCTION | NIHON NOHYAKU CO., LTD. (JP) | 2002-06-18 | — | — | US | disclosed |
| EP-1070715-A1 | ARYLPIPERIDINE DERIVATIVES AND USE THEREOF | Nihon Nohyaku Co., Ltd. (JP) | 2001-01-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020156283-A1 | Arylpiperidine derivatives and use thereof | DRD1, DRD4, DRD2 | ALDH1A1 207/4885MEN1 4032/4885KMT2A 719/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.