Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | MLYCD | O95822 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14376197 | 0.81 | TP53 (0.50) | TP53MLYCDALDH1A1HPGDKDM4E | |
| SCHEMBL6978676 | 0.76 | F2 (0.44) | TP53F2ALDH1A1HPGDKDM4E | |
| SCHEMBL22652241 | 0.76 | F2 (0.52) | TP53F2ALDH1A1HPGDKDM4E | |
| SCHEMBL28322738 | 0.75 | ALDH1A1 (0.62) | MLYCDALDH1A1HPGDKDM4ENPC1 | |
| SCHEMBL6181512 | 0.74 | F2 (0.71) | TP53F2ALDH1A1HPGDKDM4E | |
| SCHEMBL12527195 | 0.74 | CA2 (0.46) | TP53ALDH1A1HPGDKDM4ENPC1 | |
| SCHEMBL28278838 | 0.73 | MLYCD (0.62) | TP53MLYCDALDH1A1HPGDEGFR | |
| SCHEMBL23747987 | 0.72 | TP53 (0.58) | TP53MLYCDHPGDEGFRERBB2 | |
| SCHEMBL1807966 | 0.70 | CXCR4 (0.40) | F2 | |
| SCHEMBL7123985 | 0.70 | TP53 (0.82) | TP53MLYCDALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2004502669-A | — | — | 2004-01-29 | — | — | JP | claimed |
| EP-1353898-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | Elan Pharmaceuticals, Inc. (US) | 2003-10-22 | — | — | EP | claimed |
| WO-2002002512-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2002-01-10 | — | — | WO | claimed |
| EP-1242479-B1 | HIGH-MOLECULAR POLYPROPYLENE WITH A BROAD DISTRIBUTION OF THE MOLECULAR WEIGHT AND A SHORT ISOTACTIC SEQUENCE LENGTH | BASELL POLYOLEFINE GMBH (DE) | 2004-08-11 | — | — | EP | disclosed |
| EP-0856523-B1 | Process for the preparation of a metallocene catalyst system | BASELL POLYOLEFINE GMBH (DE) | 2004-07-14 | — | — | EP | disclosed |
| EP-1042371-B1 | SUPPORTED CATALYST SYSTEM FOR THE POLYMERISATION OF OLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2003-10-01 | — | — | EP | disclosed |
| EP-0859800-B1 | SUPPORTED CATALYST SYSTEM, PROCESS FOR ITS PRODUCTION AND ITS USE IN POLYMERISING OLEFINES | BASELL POLYOLEFINE GMBH (DE) | 2003-07-23 | — | — | EP | disclosed |
| EP-0780402-B1 | Supported catalyst system, process for production of the same and the use thereof for the polymerization of olefins | BASELL POLYOLEFINE GMBH (DE) | 2003-04-23 | — | — | EP | disclosed |
| EP-1003753-B1 | COMPOUNDS CONTAINING BORON AND ALUMINIUM | BASELL POLYOLEFINE GMBH (DE) | 2003-03-05 | — | — | EP | disclosed |
| EP-0856523-A1 | Process for the preparation of a metallocene catalyst system | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-08-05 | — | — | EP | disclosed |
| EP-0811640-A1 | Supported catalyst system, process for its preparation and its use in the polymerization of olefins | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-12-10 | — | — | EP | disclosed |
| EP-0780402-A1 | Supported catalyst system, process for production of the same and the use thereof for the polymerization of olefins | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-06-25 | — | — | EP | disclosed |