Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MYC | P01106 | 1/20 | 0.41 |
| ▸ | MAX | P61244 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL688777 | 0.87 | GPR35 (0.51) | GPR35ALDH1A1KMT2AGAAL3MBTL1 | |
| SCHEMBL689300 | 0.85 | GPR35 (0.49) | GPR35ALDH1A1KMT2AGAAL3MBTL1 | |
| SCHEMBL30311924 | 0.85 | GPR35 (0.49) | GPR35ALDH1A1KMT2AGAAL3MBTL1 | |
| SCHEMBL688882 | 0.85 | MAPT (0.57) | GPR35ALDH1A1KMT2AGAAL3MBTL1 | |
| SCHEMBL30629527 | 0.85 | ALDH1A1 (0.56) | GPR35ALDH1A1KMT2AGAAL3MBTL1 | |
| SCHEMBL11445926 | 0.85 | ALDH1A1 (0.56) | GPR35ALDH1A1KMT2AGAAL3MBTL1 | |
| SCHEMBL688699 | 0.84 | ALDH1A1 (0.58) | GPR35ALDH1A1KMT2AGAAL3MBTL1 | |
| SCHEMBL11633939 | 0.83 | GPR35 (0.47) | GPR35ALDH1A1KMT2AGAAL3MBTL1 | |
| SCHEMBL11535897 | 0.81 | GPR35 (0.61) | GPR35ALDH1A1KMT2AGAAL3MBTL1 | |
| SCHEMBL11455249 | 0.81 | GPR35 (0.52) | GPR35ALDH1A1KMT2AGAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953148-B1 | HETEROCYCLIC AMIDE COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL (JP) | 2012-02-29 | — | — | EP | disclosed |
| US-7915267-B2 | Heterocyclic amide compound and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-03-29 | — | — | US | disclosed |