Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 5/20 | 0.49 |
| ▸ | PTPRC | P08575 | 1/20 | 0.48 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | PTPRA | P18433 | 1/20 | 0.48 |
| ▸ | PTPRB | P23467 | 1/20 | 0.48 |
| ▸ | PTPRE | P23469 | 1/20 | 0.48 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MYC | P01106 | 1/20 | 0.43 |
| ▸ | MAX | P61244 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30311924 | 1.00 | GPR35 (0.49) | GPR35PTPRCPTPN2PTPN1PTPRA | |
| SCHEMBL688777 | 0.86 | GPR35 (0.51) | GPR35PTPN1ALDH1A1KMT2AGAA | |
| SCHEMBL689127 | 0.85 | GPR35 (0.50) | GPR35ALDH1A1KMT2AGAAL3MBTL1 | |
| SCHEMBL11445926 | 0.84 | ALDH1A1 (0.56) | GPR35PTPN1ALDH1A1KMT2AGAA | |
| SCHEMBL30629527 | 0.84 | ALDH1A1 (0.56) | GPR35PTPN1ALDH1A1KMT2AGAA | |
| SCHEMBL688882 | 0.84 | MAPT (0.57) | GPR35PTPN1ALDH1A1KMT2AGAA | |
| SCHEMBL688699 | 0.83 | ALDH1A1 (0.58) | GPR35ALDH1A1KMT2AGAAL3MBTL1 | |
| SCHEMBL11633939 | 0.82 | GPR35 (0.47) | GPR35ALDH1A1KMT2AGAAL3MBTL1 | |
| SCHEMBL11455249 | 0.80 | GPR35 (0.52) | GPR35PTPN1ALDH1A1KMT2AGAA | |
| SCHEMBL11535897 | 0.80 | GPR35 (0.61) | GPR35ALDH1A1KMT2AGAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115943144-A | Compound serving as PAK4 kinase inhibitor and preparation method and application thereof | 成都海博为药业有限公司 | 2023-04-07 | — | — | CN | disclosed |
| CN-114075175-A | Compound serving as PAK4 kinase inhibitor and preparation method and application thereof | 成都海博为药业有限公司 | 2022-02-22 | — | — | CN | disclosed |
| EP-1953148-B1 | HETEROCYCLIC AMIDE COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL (JP) | 2012-02-29 | — | — | EP | disclosed |
| US-7915267-B2 | Heterocyclic amide compound and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-03-29 | — | — | US | disclosed |