Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.52 |
| ▸ | CASR | P41180 | 10/20 | 0.46 |
| ▸ | METAP2 | P50579 | 2/20 | 0.44 |
| ▸ | METAP1 | P53582 | 1/20 | 0.44 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.42 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6891284 | 1.00 | EPHX1 (0.52) | EPHX1CASRMETAP2METAP1GABBR2 | |
| SCHEMBL6890690 | 0.83 | EPHX1 (0.41) | EPHX1METAP2METAP1 | |
| SCHEMBL6890696 | 0.83 | EPHX1 (0.41) | EPHX1METAP2METAP1 | |
| SCHEMBL6898069 | 0.83 | EPHX1 (0.41) | EPHX1METAP2METAP1 | |
| SCHEMBL6896239 | 0.76 | GABBR2 (0.45) | EPHX1METAP2METAP1GABBR2GABBR1 | |
| SCHEMBL6896230 | 0.76 | GABBR2 (0.45) | EPHX1METAP2METAP1GABBR2GABBR1 | |
| SCHEMBL6897414 | 0.76 | METAP2 (0.49) | EPHX1METAP2METAP1BCHE | |
| SCHEMBL6897426 | 0.76 | METAP2 (0.49) | EPHX1METAP2METAP1BCHE | |
| SCHEMBL27766100 | 0.75 | CYP1A2 (0.41) | EPHX1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL27653549 | 0.73 | HTR2A (0.46) | CASRHTR2AHTR2CHTR2BSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1317461-B1 | 4-CYCLOHEXYL-1,3,2-OXAZABOROLIDINE CHIRAL ACCESSORIES | SCHERING CORP (US) | 2004-11-03 | — | — | EP | disclosed |
| EP-1317461-A1 | 4-CYCLOHEXYL-1,3,2-OXAZABOROLIDINE CHIRAL ACCESSORIES | SCHERING CORPORATION (US) | 2003-06-11 | — | — | EP | disclosed |
| US-6509472-B2 | For use in enantioselective reduction of prochiral ketones to chiral secondary alcohols | SCHERING CORPORATION | 2003-01-21 | — | — | US | disclosed |
| WO-2002022623-A1 | 4-CYCLOHEXYL-1,3,2-OXAZABOROLIDINE CHIRAL ACCESSORIES | SCHERING CORPORATION (US) | 2002-03-21 | — | — | WO | disclosed |