Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 7/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.44 |
| ▸ | METAP1 | P53582 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | ACP3 | P15309 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6897426 | 1.00 | METAP2 (0.49) | METAP2EPHX1METAP1TSHRSLC18A2 | |
| SCHEMBL6898450 | 0.77 | METAP2 (0.44) | METAP2EPHX1METAP1ACP3 | |
| SCHEMBL6898442 | 0.77 | METAP2 (0.44) | METAP2EPHX1METAP1ACP3 | |
| SCHEMBL6890696 | 0.77 | EPHX1 (0.41) | METAP2EPHX1METAP1TSHR | |
| SCHEMBL6898069 | 0.77 | EPHX1 (0.41) | METAP2EPHX1METAP1TSHR | |
| SCHEMBL6890690 | 0.77 | EPHX1 (0.41) | METAP2EPHX1METAP1TSHR | |
| SCHEMBL6891293 | 0.76 | EPHX1 (0.52) | METAP2EPHX1METAP1BCHE | |
| SCHEMBL6891284 | 0.76 | EPHX1 (0.52) | METAP2EPHX1METAP1BCHE | |
| SCHEMBL820686 | 0.73 | CYP1A2 (0.41) | ACP3 | |
| SCHEMBL27633095 | 0.73 | CYP1A2 (0.41) | ACP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1317461-B1 | 4-CYCLOHEXYL-1,3,2-OXAZABOROLIDINE CHIRAL ACCESSORIES | SCHERING CORP (US) | 2004-11-03 | — | — | EP | disclosed |
| EP-1317461-A1 | 4-CYCLOHEXYL-1,3,2-OXAZABOROLIDINE CHIRAL ACCESSORIES | SCHERING CORPORATION (US) | 2003-06-11 | — | — | EP | disclosed |
| US-6509472-B2 | For use in enantioselective reduction of prochiral ketones to chiral secondary alcohols | SCHERING CORPORATION | 2003-01-21 | — | — | US | disclosed |
| WO-2002022623-A1 | 4-CYCLOHEXYL-1,3,2-OXAZABOROLIDINE CHIRAL ACCESSORIES | SCHERING CORPORATION (US) | 2002-03-21 | — | — | WO | disclosed |