Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CTSB | P07858 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | MGLL | Q99685 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11192692 | 0.88 | LMNA (0.56) | MEN1KMT2AGAAALDH1A1PKM | |
| Hydrochloric Acid SCHEMBL11196111 | 0.85 | LMNA (0.53) | MEN1KMT2AGAACYP1A2ALDH1A1 | |
| SCHEMBL3152366 | 0.84 | MEN1 (0.58) | MEN1KMT2AALDH1A1POLBMAPT | |
| SCHEMBL3865782 | 0.84 | LMNA (0.59) | MEN1KMT2ACYP1A2ALDH1A1PKM | |
| SCHEMBL29358878 | 0.84 | CTSB (0.59) | MEN1KMT2AALDH1A1PKMLMNA | |
| SCHEMBL9609632 | 0.82 | ALDH1A1 (0.51) | MEN1KMT2AALDH1A1PKMLMNA | |
| SCHEMBL2209503 | 0.82 | LMNA (0.60) | MEN1KMT2AGAACYP1A2ALDH1A1 | |
| SCHEMBL14357296 | 0.81 | MEN1 (0.55) | MEN1KMT2AGAAALDH1A1PKM | |
| SCHEMBL3171647 | 0.80 | KCNJ1 (0.58) | MEN1KMT2AALDH1A1PKMSMN1; SMN2 | |
| SCHEMBL15687902 | 0.80 | MEN1 (0.48) | MEN1KMT2AGAAALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6762180-B1 | Substituted indolines which inhibit receptor tyrosine kinases | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2004-07-13 | — | — | US | disclosed |