Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | PLK1 | P53350 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10321382 | 1.00 | KDM4E (0.51) | KDM4EGLAGAAMEN1KMT2A | |
| SCHEMBL10320703 | 1.00 | KDM4E (0.51) | KDM4EGLAGAAMEN1KMT2A | |
| SCHEMBL25026637 | 0.92 | KDM4E (0.51) | KDM4EGLAGAAMEN1KMT2A | |
| SCHEMBL719936 | 0.89 | MEN1 (0.52) | KDM4EGLAGAAMEN1KMT2A | |
| SCHEMBL11131278 | 0.86 | KDM4E (0.58) | KDM4EGLAGAAMEN1KMT2A | |
| SCHEMBL11218218 | 0.83 | ALOX15 (0.56) | KDM4EGLAMEN1KMT2ALMNA | |
| SCHEMBL25027431 | 0.81 | KDM4E (0.42) | KDM4EGLAGAAMEN1KMT2A | |
| SCHEMBL4382570 | 0.80 | MAPT (0.64) | KDM4EGLAGAAMEN1KMT2A | |
| SCHEMBL2437637 | 0.80 | MAPT (0.64) | KDM4EGLAGAAMEN1KMT2A | |
| SCHEMBL24319428 | 0.80 | KDM4E (0.53) | KDM4EGLAGAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117377651-B | Cationic lipid with side chain containing functional groups and application thereof | 厦门赛诺邦格生物科技股份有限公司 | 2025-04-01 | — | — | CN | disclosed |
| US-20250034080-A1 | CATIONIC LIPID CONTAINING SIDE-CHAIN FUNCTIONAL GROUPS AND APPLICATION THEREOF | XIAMEN SINOPEG BIOTECH CO., LTD. (CN) | 2025-01-30 | — | — | US | disclosed |
| EP-4458805-A1 | CATIONIC LIPID CONTAINING FUNCTIONAL GROUP ON SIDE CHAIN, AND USE THEREOF | Xiamen Sinopeg Biotech Co., Ltd. (CN) | 2024-11-06 | — | — | EP | disclosed |
| WO-2023126006-A1 | CATIONIC LIPID CONTAINING FUNCTIONAL GROUP ON SIDE CHAIN, AND USE THEREOF | 厦门赛诺邦格生物科技股份有限公司 | 2023-07-06 | — | — | WO | disclosed |
| CN-102421778-B | Dihydropteridinone derivatives, preparation process and pharmaceutical use thereof | JIANGSU HENGRUI MEDICINE CO | 2013-10-16 | — | — | CN | disclosed |
| CN-102702068-A | 3-pyrrolo-cyclohexylidene-2-dihydroindolone derivative, and application of 3-pyrrolo-cyclohexylidene-2-dihydroindolone derivative | JIANGSU SIMCERE PHARM RES CO | 2012-10-03 | — | — | CN | disclosed |
| CN-101389624-B | 3-pyrrolocyclohexylidene-2-indolinone derivative and application thereof | JIANGSU SIMCERE PHARM RES CO | 2012-10-03 | — | — | CN | disclosed |
| EP-2123649-B1 | 3-PYRROLO-CYCLOHEXYLENE-2-DIHYDRO-INDOLINONE DERIVATIVES AND USES THEREOF | JIANGSU SIMCERE PHARMACEUTICAL R & D CO LTD (CN) | 2012-02-29 | — | — | EP | disclosed |
| US-8084621-B2 | 3-Pyrrolo[b]cyclohexylene-2-dihydroindolinone derivatives and uses thereof | Jiangsu Simcere Pharmaceutical R&D Co. Ltd. (CN) | 2011-12-27 | — | — | US | disclosed |
| US-8084621-B2 | 3-Pyrrolo[b]cyclohexylene-2-dihydroindolinone derivatives and uses thereof | Jiangsu Simcere Pharmaceutical R&D Co. Ltd. (CN) | 2011-12-27 | — | — | US | disclosed |
| CN-102020643-A | dihydropteridine ketone derivative, and preparation method and medicinal application thereof | SHANGHAI HENGRUI MEDICINE CO LTD | 2011-04-20 | — | — | CN | disclosed |
| US-20100160318-A1 | 3-Pyrrolo[b]Cyclohexylene-2-Dihydroindolinone Derivatives and Uses Thereof | JIANGSU SIMCERE PHARMACEUTICAL R&D CO., LTD. (CN) | 2010-06-24 | — | — | US | disclosed |
| EP-2123649-A1 | 3-PYRROLO-CYCLOHEXYLENE-2-DIHYDRO-INDOLINONE DERIVATIVES AND USES THEREOF | Jiangsu Simcere Pharmaceutical R&D Co., Ltd. (CN) | 2009-11-25 | — | — | EP | disclosed |
| CN-101200446-A | 3-pyrrole ring caproic subunit-2-dihydroindolone derivatives and uses thereof | JIANGSU SIMCERE PHARMACEUTICAL (CN) | 2008-06-18 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100160318-A1 | 3-Pyrrolo[b]Cyclohexylene-2-Dihydroindolinone Derivatives and Uses Thereof | PTK2B, DMPK, STK25 | KDM4E 1929/4885GLA 2689/4885GAA 1305/4885 |
| US-20250034080-A1 | CATIONIC LIPID CONTAINING SIDE-CHAIN FUNCTIONAL GROUPS AND APPLICATION THEREOF | PHOSPHO1, LIPA, SLC7A1 | KDM4E 2894/4885GLA 1992/4885GAA 278/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.