Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | ATM | Q13315 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3254341 | 0.86 | HPGD (0.50) | HPGDCYP1A2CYP3A4CYP2D6MAPT | |
| SCHEMBL9709992 | 0.85 | CYP1A2 (0.49) | HPGDCYP1A2CYP3A4CYP2D6MAPT | |
| SCHEMBL6673408 | 0.82 | CYP1A2 (0.47) | HPGDCYP1A2CYP3A4CYP2D6MAPT | |
| SCHEMBL6564104 | 0.82 | MAPT (0.47) | HPGDCYP1A2CYP3A4CYP2D6MAPT | |
| SCHEMBL7807426 | 0.81 | LMNA (0.47) | HPGDCYP1A2CYP3A4CYP2D6MAPT | |
| SCHEMBL9709981 | 0.81 | CYP1A2 (0.46) | HPGDCYP1A2CYP3A4CYP2D6MAPT | |
| SCHEMBL9709898 | 0.81 | IKBKB (0.49) | HPGDCYP1A2CYP3A4CYP2D6MAPT | |
| SCHEMBL7962657 | 0.80 | ALDH1A1 (0.53) | HPGDCYP1A2CYP3A4CYP2D6MAPT | |
| SCHEMBL6152062 | 0.78 | MAPT (0.43) | HPGDCYP1A2CYP3A4CYP2D6MAPT | |
| SCHEMBL19437582 | 0.77 | ALDH1A1 (0.52) | HPGDCYP1A2CYP3A4CYP2D6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040082079-A1 | Low affinity screening method | GRAFFINITY PHARMACEUTICALS AG. (DE) | 2004-04-29 | — | — | US | disclosed |
| EP-1360489-A1 | LOW AFFINITY SCREENING METHOD | Graffinity Pharmaceuticals Aktiengesellschaft (DE) | 2003-11-12 | — | — | EP | disclosed |
| WO-2002063299-A1 | LOW AFFINITY SCREENING METHOD | GRAFFINITY PHARMACEUTICALS AG (DE) | 2002-08-15 | — | — | WO | disclosed |
| US-5097068-A | For preparing herbicidal, substituted benzoyl cyclohexanediones | ICI AMERICAS, INC. (US) | 1992-03-17 | — | — | US | disclosed |
| US-4966998-A | FOR PREPARING HERBICIDES, TRISUBSTITUTED BENZOYL CYCLOHEXANEDIONES | ICI AMERICAS INC. (US) | 1990-10-30 | — | — | US | disclosed |
| CN-1009086-B | Process for preparing tri-substituted benzoic acid intermediates | STAUFFER CHEMICAL CO (US) | 1990-08-08 | — | — | CN | disclosed |
| US-4898973-A | Trisubstituted benzoic acid intermediates | ICI AMERICAS INC. (US) | 1990-02-06 | — | — | US | disclosed |
| EP-0195247-B1 | TRISUBSTITUTED BENZOIC ACID INTERMEDIATES | STAUFFER CHEMICAL COMPANY (US) | 1989-02-08 | — | — | EP | disclosed |
| CN-86101277-A | Trisubstituted phenylformic acid intermediates preparation | — | 1986-11-19 | — | — | CN | disclosed |
| EP-0195247-A1 | Trisubstituted benzoic acid intermediates | STAUFFER CHEMICAL COMPANY (US) | 1986-09-24 | — | — | EP | disclosed |