Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | SELL | P14151 | 1/20 | 0.36 |
| ▸ | SELP | P16109 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6891924 | 0.86 | HPGD (0.64) | HPGDCYP1A2CYP3A4CYP2D6MAPT | |
| SCHEMBL7573192 | 0.83 | LMNA (0.45) | HPGDCYP1A2CYP3A4CYP2D6MAPT | |
| SCHEMBL5101279 | 0.83 | MAPT (0.47) | HPGDCYP1A2CYP3A4CYP2D6MAPT | |
| SCHEMBL9709992 | 0.82 | CYP1A2 (0.49) | HPGDCYP1A2CYP3A4CYP2D6MAPT | |
| SCHEMBL7978923 | 0.81 | ALDH1A1 (0.42) | HPGDCYP1A2CYP3A4CYP2D6MAPT | |
| SCHEMBL6564104 | 0.80 | MAPT (0.47) | HPGDCYP1A2CYP3A4CYP2D6MAPT | |
| SCHEMBL6673408 | 0.80 | CYP1A2 (0.47) | HPGDCYP1A2CYP3A4CYP2D6MAPT | |
| SCHEMBL9709981 | 0.78 | CYP1A2 (0.46) | HPGDCYP1A2CYP3A4CYP2D6MAPT | |
| SCHEMBL9709898 | 0.78 | IKBKB (0.49) | HPGDCYP1A2CYP3A4CYP2D6MAPT | |
| SCHEMBL6564003 | 0.76 | DDR1 (0.43) | HPGDCYP1A2CYP3A4CYP2D6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1427701-B1 | 3-AMINO CARBONYL-SUBSTITUTED BENZOYLCYCLOHEXANEDIONES THAT CAN BE USED AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2010-05-05 | — | — | EP | disclosed |
| US-7390827-B2 | 3-aminocarbonyl substituted benzoylpyrazolones | BAYER CROPSCIENCE AG (DE) | 2008-06-24 | — | — | US | disclosed |
| EP-1529034-B1 | BENZOYLPYRAZOLONES SUBSTITUTED BY 3-AMINOCARBONYL | BAYER CROPSCIENCE AG (DE) | 2008-02-20 | — | — | EP | disclosed |
| EP-1379497-B1 | DERIVATIVES OF BENZOYLCYCLOHEXANEDIONE AND THEIR USE AS HERBICIDES | BAYER CROPSCIENCE GMBH (DE) | 2007-01-17 | — | — | EP | disclosed |
| EP-1315697-B1 | HERBICIDAL BENZOYL CYCLOHEXANE DIONE | BAYER CROPSCIENCE GMBH (DE) | 2006-03-22 | — | — | EP | disclosed |
| CN-1235877-C | Substd. N-phenyl-2-hydroxy-2-methyl-3,3,3-trifluoropropanamide derivs. which elevate pyruvate dehydrogenase activity | ASTRAZENECA AB (SE) | 2006-01-11 | — | — | CN | disclosed |
| US-20050267184-A1 | 3-Aminocarbonyl substituted benzoylpyrazolones | BAYER CROPSCIENCE GMBH (DE) | 2005-12-01 | — | — | US | disclosed |
| US-6930208-B2 | 3-Keto- or 3- oxime-ether-substituted benzoylcyclohexanediones | BAYER CROPSCIENCE GMBH (DE) | 2005-08-16 | — | — | US | disclosed |
| US-6894070-B2 | 3-Aminocarbonyl substituted benzoylpyrazolones | BAYER CROPSCIENCE GMBH (DE) | 2005-05-17 | — | — | US | disclosed |
| EP-1529034-A1 | BENZOYLPYRAZOLONES SUBSTITUTED BY 3-AMINOCARBONYL | Bayer CropScience GmbH (DE) | 2005-05-11 | — | — | EP | disclosed |
| CN-1387509-A | Substd. N-phenyl-2-hydroxy-2-methyl-3,3,3-trifluoropropanamide derivs. which elevate pyruvate dehydrogenase activity | ASTRAZENECA AB (SE) | 2002-12-25 | — | — | CN | disclosed |
| US-20020165095-A1 | Herbicidally active benzoylcyclohexanediones | BAYER CROPSCIENCE GMBH (DE) | 2002-11-07 | — | — | US | disclosed |
| WO-2002081434-A1 | DERIVATIVES OF BENZOYLCYCLOHEXANEDIONE AND THEIR USE AS HERBICIDES | BAYER CROPSCIENCE GMBH (DE) | 2002-10-17 | — | — | WO | disclosed |
| US-5097068-A | For preparing herbicidal, substituted benzoyl cyclohexanediones | ICI AMERICAS, INC. (US) | 1992-03-17 | — | — | US | disclosed |
| US-4966998-A | FOR PREPARING HERBICIDES, TRISUBSTITUTED BENZOYL CYCLOHEXANEDIONES | ICI AMERICAS INC. (US) | 1990-10-30 | — | — | US | disclosed |
| CN-1009086-B | Process for preparing tri-substituted benzoic acid intermediates | STAUFFER CHEMICAL CO (US) | 1990-08-08 | — | — | CN | disclosed |
| US-4898973-A | Trisubstituted benzoic acid intermediates | ICI AMERICAS INC. (US) | 1990-02-06 | — | — | US | disclosed |
| EP-0195247-B1 | TRISUBSTITUTED BENZOIC ACID INTERMEDIATES | STAUFFER CHEMICAL COMPANY (US) | 1989-02-08 | — | — | EP | disclosed |
| CN-86101277-A | Trisubstituted phenylformic acid intermediates preparation | — | 1986-11-19 | — | — | CN | disclosed |
| EP-0195247-A1 | Trisubstituted benzoic acid intermediates | STAUFFER CHEMICAL COMPANY (US) | 1986-09-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020165095-A1 | Herbicidally active benzoylcyclohexanediones | DDT, CBR1, CBR3 | HPGD 1668/4885CYP1A2 68/4885CYP3A4 414/4885 |
| US-20050267184-A1 | 3-Aminocarbonyl substituted benzoylpyrazolones | CBR3, CYCS, MT-CO2 | HPGD 2149/4885CYP1A2 9/4885CYP3A4 72/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.