SCHEMBL6892089

SCHEMBL6892089

CC(C)(C)OC(=O)N1CCC(CN2CCN(S(=O)(=O)c3cc4cc(Cl)ccc4o3)CC2=O)CC1

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MMP13 P45452 1/20 0.43
STS P08842 4/20 0.40
GPR119 Q8TDV5 5/20 0.39
MAPT P10636 1/20 0.38
FPR2 P25090 1/20 0.38
UTS2R Q9UKP6 1/20 0.38
F10 P00742 1/20 0.38
TGFBR1 P36897 1/20 0.37
KDM4E B2RXH2 1/20 0.37
PKM P14618 1/20 0.37
CNR1 P21554 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
F13A1 P00488 1/20 0.37
TGM2 P21980 1/20 0.37
TGM1 P22735 1/20 0.37
TGM3 Q08188 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6895114 0.85 STS (0.46) STSGPR119MAPTF10KDM4E
Hydrochloric Acid SCHEMBL6894725 0.81 DRD2 (0.45) F10KDM4E
SCHEMBL4388695 0.81 F10 (0.54) F10
SCHEMBL7053070 0.80 STS (0.43) STSGPR119F10CNR1
SCHEMBL6892977 0.79 UTS2R (0.41) STSGPR119MAPTFPR2UTS2R
SCHEMBL7046610 0.78 GPR119 (0.42) STSGPR119MAPTFPR2F13A1
SCHEMBL6888115 0.78 F10 (0.44) F10
Hydrochloric Acid SCHEMBL6895587 0.78 F10 (0.43) F10
SCHEMBL6887446 0.78 GPR119 (0.47) STSGPR119F10TGFBR1F13A1
SCHEMBL7048729 0.78 STS (0.46) STSGPR119MAPTF10TGFBR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6680312-B2 FOR THERAPY OF CARDIAC INFARCTION, CEREBRAL THROMBOSIS; INHIBIT ACTIVATED COAGULATION FACTOR X (FXA) TO SHOW ANTI-COAGULANT ACTIVITY TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2004-01-20 US disclosed
US-20020193382-A1 Sulfonamide derivatives, their production and use TAKEDA PHARMACEUTICAL COMPANY, LIMITED (JP) 2002-12-19 US disclosed
US-6403595-B1 ANTICOAGULANTS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2002-06-11 US disclosed
EP-1054005-A1 SULFONAMIDE DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND UTILIZATION THEREOF Takeda Chemical Industries, Ltd. (JP) 2000-11-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020193382-A1 Sulfonamide derivatives, their production and use F12, F11, F2 MMP13 805/4885STS 13/4885GPR119 2981/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.