⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30547298 | 0.87 | EGLN1 (0.37) | — | |
| SCHEMBL20759820 | 0.82 | FFAR3 (0.39) | — | |
| Ether SCHEMBL9191338 | 0.79 | EGLN1 (0.41) | — | |
| SCHEMBL31683981 | 0.79 | FFAR3 (0.36) | — | |
| SCHEMBL23891795 | 0.78 | — | — | |
| SCHEMBL2562258 | 0.77 | KDM4E (0.41) | — | |
| SCHEMBL29454886 | 0.76 | TSHR (0.39) | — | |
| SCHEMBL2362892 | 0.76 | ADRA1A (0.48) | — | |
| SCHEMBL2231175 | 0.75 | — | — | |
| SCHEMBL30648987 | 0.74 | ALDH1A1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6723515-B2 | POLYAMIDE FOR USE TOOL IN THE ADJUSTMENT OF THE MIGRATION OF NUCLEOTIDE SEQUENCES DURING ELECTROPHORESIS | NORTHWESTERN UNIVERSITY | 2004-04-20 | — | — | US | disclosed |
| US-20030088056-A1 | DNA mobility modifier | UNITED STATES DEPARTMENT OF ENERGY | 2003-05-08 | — | — | US | disclosed |
| US-6455682-B1 | POLYAMIDE COMPOUND FOR USE IN DETERMINING THE SEQUENCE OF A TARGET POLYNUCLEOTIDE | NORTHWESTERN UNIVERSITY | 2002-09-24 | — | — | US | disclosed |
| WO-2000043547-A1 | DNA MOBILITY MODIFIER | NORTHWESTERN UNIVERSITY (US) | 2000-07-27 | — | — | WO | disclosed |